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Urinary Bladder Cancer clinical trials

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NCT ID: NCT06156787 Completed - Clinical trials for Urinary Bladder Cancer

Patterns of Urinary Bladder Cancer in Darfur, Suda

Start date: November 1, 2020
Phase:
Study type: Observational

Background: Bladder cancer (BC) exhibits extreme heterogeneity regarding clinical outcome, etiology, histology, and geographic distribution. Recent clinical observations point to alterations in the BC pattern in the Sudan, possibly as a result of lifestyle changes brought on by the enormous migration from rural to urban locations. This study aimed to identify the pattern of bladder cancer in Darfur. Patients and Methods: A cross sectional, hospital-based study, it was conducted inNyala specialized hospital, during the period from (2020 to 2022), included one hundred and five patients with bladder mass matching the inclusion criteria were studied over the diversity of demographic data , clinical finding, pathological type and possible risk factors .

NCT ID: NCT05946369 Completed - Clinical trials for Urinary Bladder Cancer

Neutrophils to Lymphocytes Ratio in Predicting the Response to BCG in Non-muscle Invasive Bladder Cancer

Start date: May 1, 2020
Phase:
Study type: Observational

There is a relation between inflammatory cells and the prognosis of tumors (cancer colon, renal, liver, and urinary bladder). In this study, the investigators will link the Neutrophils to Lymphocytes ratio to the response to intravesical BCG therapy post trans-urethral resection of urinary bladder tumors for the non-invasive urinary bladder tumors.

NCT ID: NCT04635566 Completed - Clinical trials for Urinary Incontinence

Pharmacological Enhancement for Nocturnal Incontinence in Orthotopic Bladder Substitute

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

In this randomised trial, we hypothesised that mebeverine could enhance nocturnal continenece of Orthotopic Bladder Substitute (OBS) patients by decreasing the frequency and reduce maximum amplitude of uninhibited contractions of OBS ileum, and consequently it would increase the OBS capacity

NCT ID: NCT03998579 Completed - Clinical trials for Urinary Bladder Cancer

Physical Rehabilitation Among Patients Undergoing Radical Cystectomy Due to Urinary Bladder Cancer

CanMoRe
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The main objective of the CanMoRe study is to evaluate the impact of a standardized and individually adapted exercise intervention in Primary Health Care aiming at improving physical function (primary outcome) and habitual physical activity, health related quality of life, fatigue and psychological well-being in patients undergoing radical cystectomy due to urinary bladder cancer.

NCT ID: NCT03636256 Completed - Bladder Cancer Clinical Trials

Evaluation of NanoDoce® in Participants With Urothelial Carcinoma

Start date: April 2, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This is a clinical trial studying the administration of NanoDoce as a direct injection to the bladder wall immediately after tumor resection and as an intravesical instillation. All participants will receive NanoDoce, and will be evaluated for safety and tolerability, as well as the potential effects of NanoDoce on urothelial carcinoma.

NCT ID: NCT03433924 Completed - Clinical trials for Urinary Bladder Cancer

An Epidemiologic Study on PD-L1 Expression Combined With Clinical Observation in the Chinese MIUBC Patients.

POLARIS
Start date: May 18, 2020
Phase:
Study type: Observational

The Primary Objective of this observational study is to investigate the prevalence of high PD-L1 expression in Chinese MIUBC patients.

NCT ID: NCT02897765 Completed - Lung Cancer Clinical Trials

A Personal Cancer Vaccine (NEO-PV-01) w/ Nivolumab for Patients With Melanoma, Lung Cancer or Bladder Cancer

Start date: October 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate if the treatment with NEO-PV-01 + adjuvant in combination with nivolumab is safe and useful for patients with certain types of cancer. The study also will investigate if NEO-PV-01 + adjuvant with nivolumab may represent a substantial improvement over other available therapies such as nivolumab alone. All eligible patients will receive NEO-PV-01 + adjuvant and nivolumab while on this trial.

NCT ID: NCT02722538 Completed - Clinical trials for Urinary Bladder Cancer

Safety and Tolerability of GemRIS 225 mg in Subjects With Muscle-Invasive Bladder Cancer

Start date: May 31, 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if TAR-200, an investigational drug-delivery system, is safe and tolerable in patients with muscle-invasive bladder cancer (MIBC) between diagnosis and radical cystectomy (RC).

NCT ID: NCT02720367 Completed - Clinical trials for Urinary Bladder Cancer

Safety and Tolerability of TAR-200 mg in Subjects With Non-Muscle-Invasive Bladder Cancer

Start date: January 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if TAR-200, an investigational drug-delivery system is safe and tolerable in patients with recurrent low or intermediate risk non-muscle-invasive bladder cancer (NMIBC) between diagnosis and transurethral resection of bladder tumors (TURBT)

NCT ID: NCT02437539 Completed - Breast Cancer Clinical Trials

Evaluation of a New Radiotracer (68Ga-NOTA-AE105) for Diagnosing Aggressive Cancer With Positron Emission Tomography

uPAR-PET
Start date: May 2015
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to test a new radiotracer called 68Ga-NOTA-AE105 for PET imaging of uPAR (urokinase plasminogen activator receptor). The tracer has the potential of identifying the invasive cancer phenotype, thereby distinguishing between aggressive and less aggressive tumors. This is a first in human study to test the radiotracer in cancer patients. The biodistribution and tumor uptake will be evaluated by repeated PET imaging (10 minutes, 1 hour and 2 hours post injection).