Type2 Diabetes Mellitus Clinical Trial
Official title:
Heart Rate Variability and Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients
Several studies have investigated an association between cardiac autonomic neuropathy (CAN)
and albuminuria, glomerular filtration rate, or both, and hypothesized that CAN is involved
in the pathogenesis of nephropathy. However, most of these studies had focused on Caucasians
and were limited to a small number of patients with type 1 diabetes mellitus, or had used a
conventional Ewing battery of tests based on dynamic cardiovascular maneuvers.Yet, there is
consistent data showing that Asian diabetic populations, including the Chinese, have a
higher risk of renal complications than Caucasians do.
The present study investigated an association between heart rate variability (HRV)
parameters and diabetic kidney disease (DKD) in Chinese type 2 diabetes mellitus (T2DM)
patients, specifically through time and frequency domain analyses of HRV and urine albumin
creatinine ratio (UACR) or estimated glomerular filtration rate (eGFR).
present study investigated an association between HRV parameters and DKD in Chinese T2DM patients, specifically through time and frequency domain analyses of HRV and UACR or eGFR ;
Observational Model: Case-Only
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