Type1diabetes Clinical Trial
Official title:
Studies of Activity of Brown Adipose Tissue With Positron Emission Tomography Using the Tracer 18F-deoxy Glucose in Patients With Type 1 Diabetes
Brown adipose tissue has the capacity to consume large amounts of energy and has
insulin-independent glucose uptake. The investigators have recently observed an inverse
correlation between irisin levels and insulin needs of type 1 diabetes patients.
Transplantation of brown adipose tissue to insulin-deficient rats normalized their blood
glucose levels.
In this study 12 patients with long-standing type 1 diabetes (>10 years) and with variable
exogenous insulin needs will be investigated for amount of brown adipose tissue with positron
emission tomography using the tracer 18F-deoxy glucose.
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