Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT05346497 |
Other study ID # |
B2021-776R |
Secondary ID |
|
Status |
Completed |
Phase |
|
First received |
|
Last updated |
|
Start date |
January 1, 2005 |
Est. completion date |
November 1, 2021 |
Study information
Verified date |
April 2022 |
Source |
Shanghai Zhongshan Hospital |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational
|
Clinical Trial Summary
The investigators focus on the patients who underwent aortic root surgery for acute type A
aortic dissection between 2005.01-2021.11. The patients are divided into 3 groups according
to the different aortic root surgical methods(Bentall,David and root reconstruction).
Clinical data including age, gender, comorbidities, surgical informations and perioperative
informations will be collected. All patients will receive follow-ups in hospital or by
telephone.
All the informations will be analyzed by SPSS to show the difference of both perioperative
and long-term results among different surgical strategies.
Description:
Acute type A aortic dissection (ATAAD) is a rare but life threatening situation requiring
immediate intervention. Regarding emergency operation for ATAAD, an important principle is to
reconstruct the afflicted aorta to prevent fatal rupture.
For aortic root dissection, the Bentall procedure has been the standard operation and has
been proven simple and effective. However, the requirement for lifelong anticoagulation
therapy is associated with increased risk of thromboembolic and bleeding complications. Valve
sparing aortic root reimplantation (David reimplantation), which has been proven effective in
root aneurysm with satisfactory safety and long-term outcomes, is an appealing alternative to
preserve native aortic valve, especially for younger patients with intact valve function.
Aortic root reconstruction without valve surgery is also a well-used strategy for aortic root
dissection, but the long-term outcome is still controversial.
The investigators focus on the patients who underwent aortic root surgery for acute type A
aortic dissection between 2005.01-2021.11. The patients are divided into 3 groups according
to the different aortic root surgical methods(Bentall,David and root reconstruction).
Clinical data including age, gender, comorbidities, surgical informations and perioperative
informations will be collected. All patients will receive follow-ups in hospital or by
telephone.
All the informations will be analyzed by SPSS to show the difference of both perioperative
and long-term results among different surgical strategies.