Type 2 Diabetes Mellitus Clinical Trial
Official title:
Combined Resistance and Endurance Training in Patients With Type 2 Diabetes: A Pilot-study to Assess the Effects of 2 Different Resistance Protocols on Muscle Mass, Strength and Glycemic Control.
Skeletal muscle accounts for up to 40% of the total body weight and is responsible for
approximately 75% of the whole body insulin-stimulated glucose uptake. Resistance training
has been shown to improve insulin-stimulated glucose uptake in patients with T2DM. Therefore
the investigators aim to compose the effects of 2 different resistance training protocols in
combination with aerobic endurance training (AET) on muscle strength, muscle mass and
glycemic control in type 2 diabetes mellitus patients (T2DM).
The investigators aim to perform an 8 week randomized controlled training intervention in 32
T2DM patients. Patients will be randomly assigned to AET (cycle ergometer, 60-70% of heart
rate reserve) combined with hypertrophy resistance training (HRT, n=16, 2 sets, 10-12
repetitions, 70% of the one-repetition maximum) or with endurance resistance training (ERT,
n=16, 2 sets, 25-30 repetitions, 40% of the one-repetition maximum). Body composition, blood
analyses, physical work capacity and muscle strength will be measured pre- and
post-intervention.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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