Type 2 Diabetes Mellitus Clinical Trial
Official title:
A Prospective, Observational Study on the Use of Glucophage XR Therapy in the Management of Patients With Type 2 Diabetes
This was an observational, prospective, multicentric study conducted in a cohort of subjects with type 2 diabetes and prescribed with Glucophage XR therapy from hospitals or clinics in Hong Kong, Indonesia, Korea, Malaysia, Philippines and Singapore. Glucophage XR is being used in the Asia Pacific region for the treatment of subjects with type 2 diabetes. This study was designed to provide information on the day to-day experience of using Glucophage XR in the management of subjects with type 2 diabetes and its use in routine clinical practice in Asia Pacific region.
Glucophage (metformin) is the standard first line therapy for subjects with type 2 diabetes
mellitus (DM). The consensus statement from the American Diabetes Association and the
European Association for the Study of Diabetes has recommended metformin therapy in
concurrent with lifestyle intervention at diagnosis. It has been well accepted that
subjects' compliance with therapy tends to decrease as the dosage frequency increases and
hence the regimens should be simplified as far as possible to support good compliance with
therapy. The use of an extended release formulation of metformin (Glucophage XR) supports
the simplification of treatment of subjects with type 2 diabetes by allowing a once daily
administration of metformin.
OBJECTIVES
Primary objective:
- To assess the tolerability of Glucophage XR therapy when used in routine clinical
practice in subjects with type 2 diabetes
Secondary objective:
- To assess the effectiveness of Glucophage XR therapy on the maintenance of glycaemic
control
The study does not involve any active involvement of the subjects and does not require any
change from the standard medical management of the subjects. Each subject will be followed
upon starting Glucophage XR therapy and until at least 12 weeks of treatment or
discontinuation of treatment, whichever being earlier.
;
Observational Model: Cohort, Time Perspective: Prospective
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