Type 2 Diabetes Mellitus Clinical Trial
Official title:
A Multi-center, Open, Randomized, Parallel-group, 2 Arm Study to Compare the Efficacy and Safety of Amaryl®M 1/500mg Twice Daily Versus Amaryl® 4mg Both in Combination With Lantus® Once-daily Regimen in Type 2 Diabetes Mellitus Patients With Inadequate Glycemic Control
The purpose of this study is to compare the efficacy of Amaryl®M 1/500 mg twice daily versus Amaryl® 4 mg both in combination with Lantus® once-daily regimen in type 2 Diabetes Mellitus patients with inadequate glycemic control.
There are several kinds of oral antidiabetic drugs (OADs) that are used in the treatment of
patients with type 2 DM. Among them, sulfonylurea and metformin are well-established
first-line OADs. However, as the beta cell dysfunction progresses over time, patients fail
to achieve good glycemic control with OADs alone and need further treatment intensification,
usually involving the introduction of insulin either alone or in combination with OADs. Now,
an OAD combined with bedtime insulin is one of the recommended treatment options for
patients with type 2 DM and OAD failure. But, it still remains unclear which OADs are the
most effective in combination with insulin for the treatment of type 2 DM.
so, this study we will be able to verify which OADs are the most effective in combination
with insulin for the treatment of type 2 DM.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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