Clinical Trials Logo

Type 1 Diabetes clinical trials

View clinical trials related to Type 1 Diabetes.

Filter by:

NCT ID: NCT04741685 Completed - Type 1 Diabetes Clinical Trials

Clinical Efectivity of Two Different Sensor-augmented Pumps With Low Predictive Suspension Function

Start date: February 15, 2021
Phase:
Study type: Observational [Patient Registry]

Observational cross-sectional multicenter study about effectiveness of two different sensor augmented-pumps with low glucose predictive function in Type 1 Diabetes Mellitus (T1DM) adult patients in routine clinical practice.

NCT ID: NCT04730882 Active, not recruiting - Type 1 Diabetes Clinical Trials

Effect of Postprandial Hyperglycemia on Vasculature in Type 1 Diabetes and Healthy Adults

WBH001
Start date: April 6, 2021
Phase:
Study type: Observational

To the investigator's knowledge, there are no data available in the current literature regarding the acute effects of postprandial hyperglycemia and insulin timing on myocardial perfusion in people with type 1 diabetes (T1D). Observational studies using CEU in type 2 diabetes demonstrate that postprandial hyperglycemia determines myocardial perfusion defects. The investigator hypothesizes that the combination of postprandial hyperglycemia and insulin increases pulse wave velocity (i.e., aortic stiffness) and myocardial vasoconstriction, thereby reducing myocardial perfusion in T1D when compared to healthy controls. Furthermore, the investigator hypothesizes in T1D that dosing insulin before meal intake will ameliorate these cardiovascular defects.

NCT ID: NCT04721145 Completed - Type 1 Diabetes Clinical Trials

CGM Use in Poorly Controlled Youth With Type 1 Diabetes

IMPaCT
Start date: January 25, 2021
Phase: N/A
Study type: Interventional

The purpose of this prospective study is to determine if trial use of a Dexcom G6 CGM system for a 10 day wear period in high risk, poorly controlled pediatric Type 1 diabetes patients increases uptake of personal CGM use, and improves short-term time in range glucose control.

NCT ID: NCT04711382 Completed - Type 1 Diabetes Clinical Trials

The Use of Faster Acting Aspart in Type 1 Diabetes Patients

Start date: January 29, 2018
Phase:
Study type: Observational

Data on switching from traditional mealtime insulins to fast-acting insulin aspart (Fiasp) in routine clinical practice are sparse. The aim was to evaluate the efficacy and safety of switching from traditional mealtime insulin to Fiasp in a "real-world" clinical practice setting in people with type 1 diabetes in Belgium.

NCT ID: NCT04698122 Completed - Type 2 Diabetes Clinical Trials

Establishment of the Human Intestinal and Salivary Microbiota Biobank- Diabetes

BIOMIS-Diab
Start date: May 27, 2021
Phase:
Study type: Observational

This is a prospective, clinical, monocentric study aimed to collect biological samples and study microbiota from subjects suffering from type 1 diabetes mellitus, subjects suffering from type 2 diabetes mellitus and from healthy volunteers. Microbiota is a complex consortium of microorganisms, located at the mucosal level (in particular intestinal, oral and vaginal) having a key role in human health and in the onset of several diseases. Microbiota alterations have been found in several diseases (gastrointestinal, metabolic, renal, oncological, gynaecological). The study will allow to: - Provide biological samples (faeces, saliva, blood, urine) from healthy volunteers and patients suffering with diabetes mellitus 1 and 2 to the first Italian microbiota biobank; - Study microorganisms using different in vitro and in vivo techniques; - Study the link between the microbiota and the disease. This study is part of the BIOMIS project (Project Code: ARS01_01220), presented as part of the "Avviso per la presentazione di progetti di ricerca industriale e sviluppo sperimentale nelle 12 aree di specializzazione individuate dal PNR 2015-2020" and admitted to funding under the National Operational Program "Ricerca e Innovazione" 2014-2020 by directorial decree of MIUR - Department for Higher Education and Research - n. 2298 of 12 September 2018. BIOMIS includes several clinical studies that enrol patients with different pathologies to collect and store biological samples and study microbiota.

NCT ID: NCT04696640 Completed - Type 1 Diabetes Clinical Trials

Pilot Study of Remote Glucose Monitoring Among Pediatric Patients With Type 1 Diabetes

Start date: June 3, 2021
Phase: N/A
Study type: Interventional

This project explores the feasibility and utility of remote glucose monitoring for a cohort of children and adolescents with type 1 diabetes (T1D) cared for at UC Davis Health (UCDH).

NCT ID: NCT04684030 Recruiting - Type 1 Diabetes Clinical Trials

The Management of Glucose Control and Hypoglycemic Prevention Using Continuous Glucose Monitoring System in Patients With Type 1 Diabetes

Start date: August 28, 2020
Phase: N/A
Study type: Interventional

This study was designed to evaluate the glucose control and hypoglycemic prevention effect of using continuous glucose monitoring system(CGMS) in patients with type 1 diabetes. This is a prospective randomized controlled, single-center clinical study. Patients will randomized 1:1 to either CGMS or conventional self-monitoring of blood glucose (SMBG) group. After 12 weeks of applying the CGMS sensors, the improvement of parameters collected from the CGMS will be estimated in comparison with data collected from the SMBG.

NCT ID: NCT04678557 Terminated - Type 1 Diabetes Clinical Trials

A Study to Evaluate Safety, Engraftment, and Efficacy of VC-01 in Subjects With T1 Diabetes Mellitus

VC01-103
Start date: June 25, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

VC01-103 will evaluate an experimental combination product, cell replacement therapy intended to provide a functional cure to subjects with Type 1 Diabetes.

NCT ID: NCT04677699 Enrolling by invitation - Type 1 Diabetes Clinical Trials

Combined Antibody Screening for Celiac and Diabetes Evaluation

CASCADE
Start date: December 2020
Phase:
Study type: Observational

The CASCADE Study (Combined Antibody Screening for Celiac and Diabetes Evaluation) is an observational study whose primary goal is to show that population-based screening for advanced prediction of type 1 diabetes (T1D) and celiac disease (CD) is feasible to prevent diabetic ketoacidosis (DKA), improve celiac disease diagnosis, and ultimately gain public health acceptance to facilitate future prevention. It has two arms, a Birth Cohort and a Kids (cross sectional) Cohort.

NCT ID: NCT04674384 Recruiting - Obesity Clinical Trials

Manchester Intermittent and Daily Diet Type 1 Diabetes App Study (MIDDAS-Type 1)

MIDDAS T1
Start date: January 19, 2022
Phase: N/A
Study type: Interventional

To assess the safety, acceptability and feasibility of testing Intermittent Low Energy Diet (ILED) and Continuous Low Energy Diet (CLED) programmes for 12 weeks in a real life setting with people with T1D and obesity.