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Tumors clinical trials

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NCT ID: NCT00292864 Completed - Tumors Clinical Trials

Safety Assessment of One-hour Infusions of SNS-032 for the Treatment of Select Advanced Solid Tumors

Start date: January 2006
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of one-hour infusions given once daily for 5 consecutive days in a 21-day treatment cycle; to define a recommended phase 2 dose; and to learn more about the clinical activity of SNS-032.

NCT ID: NCT00279695 Active, not recruiting - Glaucoma Clinical Trials

Ultrasonic Evaluation of Ocular Tissues

Start date: January 1996
Phase: N/A
Study type: Observational

The objective of this research program is to improve diagnosis and treatment monitoring of ophthalmic disease by improving diagnostic ultrasound techniques. The program explores the use of novel signal and imaging processing techniques towards this end.

NCT ID: NCT00264004 Completed - Tumors Clinical Trials

Study to Investigate the Management of Hypertension and Efficacy of AZD2171 in Patients With Advanced Solid Tumours

Start date: November 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether doses of 30 mg and 45 mg AZD2171 can be well tolerated without significant drug withdrawal when accompanied by a suitable hypertension management strategy or dose reduction.

NCT ID: NCT00255333 Terminated - Tumors Clinical Trials

INNO-105 in Patients With Solid Tumors

Start date: November 2005
Phase: Phase 1
Study type: Interventional

The safety, tolerability and pharmacokinetics of INNO-105, an investigational anticancer drug, are being studied in patients with solid tumors.

NCT ID: NCT00248404 Completed - Tumors Clinical Trials

NB1011 Administered by Continuous Infusion in Cancers That Overexpress Thymidylate Synthase (TS)

Start date: September 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this trial is to assess the tolerability and safety of NB1011 in the treatment of patients with cancers that overexpress TS, such as ovarian, gastrointestinal, colorectal, bladder, breast, and lung cancers.

NCT ID: NCT00230217 Completed - Tumors Clinical Trials

Study of Rasburicase as Treatment or Prevention of Hyperuricemia Associated With Tumor Lysis Syndrome in Patients With Relapsed or Refractory Lymphoma, Leukemia, or Solid Tumor Malignancy

Start date: March 2004
Phase: Phase 4
Study type: Interventional

This is an open-label, multi-center study with 2 arms. The primary objective is to assess the response to treatment with rasburicase in 2 populations of adult and pediatric patients with lymphoma/leukemia/solid tumor malignancies, those previously treated with a uricolytic agent, and those not previously treated with a uricolytic agent at their first relapse or refractory disease.

NCT ID: NCT00229879 Terminated - Tumors Clinical Trials

Rare Tumor Case Review

Start date: December 2004
Phase: N/A
Study type: Observational

The purpose of this study is to do a literature review and combine all of the cases of the intrapericardial teratoma tumor and see if some conclusions can be made about this rare tumor in children.

NCT ID: NCT00222443 Completed - Tumors Clinical Trials

Pilot Study Combining Temozolomide, Oncovin, Camptosar and Oral Antibiotic in Children and Adolescents With Recurrent Malignancy

Start date: September 2004
Phase: Phase 1
Study type: Interventional

Determine toxicity and maximum tolerated dose of escalating daily protracted irinotecan, with weekly vincristine, temozolomide and vantin; to evaluate the feasibility of repetitive cycles of this chemotherapy and to estimate the response rate to this combination in children and adolescents with recurrent solid tumors and lymphomas.

NCT ID: NCT00207103 Completed - Neoplasm Metastasis Clinical Trials

MAD in Cancer Patients: Safety of BMS-582664 in Patients With Advanced or Metastatic Solid Tumors

Start date: September 2004
Phase: Phase 1
Study type: Interventional

This is a Phase I dose escalation study to determine the safety, pharmacokinetics and pharmacodynamics of BMS-582664 in patients with advanced or metastatic solid tumors.

NCT ID: NCT00207025 Terminated - Tumors Clinical Trials

A Phase I Study of BMS-275183 Given on a Daily Schedule in Patients With Advanced Malignancies

Start date: October 2004
Phase: Phase 1
Study type: Interventional

The purpose of this clinical research study is to learn about the safety and tolerability of daily BMS-275183 in patients with advanced cancer.