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NCT06141148 Clinical Trial

Clinical Presentation, and Treatment Outcomes in Tuberculous Patients in Sohag Governorate

Tuberculosis Clinical Trial

Official title:
Clinical Presentaion, and Treatment Outcomes in Tuberculous Patients in Sohag Governorate

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06141148
Other study ID # Soh-Med-23-10-012MS
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date November 1, 2023
Est. completion date December 30, 2024

Study information
Verified date November 2023
Source Sohag University
Contact mohamed mohey, resident
Phone 01110721019
Email mohamedmohie@med.sohag.edu.eg
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Tuberculosis (TB) is an infectious disease that commonly affects the lung and is caused by a bacterium called Mycobacterium Tuberculosis. The bacterium mostly affects people with impaired immunity TB becomes the second leading cause of morbidity and mortality among infectious diseases, following the emergence of the human immunodeficiency virus (HIV). HIV is the commonest risk factor for developing a life-threatening tuberculosis disease, on the other hand, HIV related immunodeficiency is worsened by TB infection.TB is among the top 10 causes of death worldwide. In2019, among 8.8 million adults who developed TB disease, 36% were women .TB has become the fifth leading cause of death among women.

Recruitment information / eligibility
Status Recruiting
Enrollment 200
Est. completion date December 30, 2024
Est. primary completion date December 30, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - age above 18ys. - confirmed diagnosis of tuberculosis. Exclusion Criteria: - childern. - not confirmed diagnosis of tuberculosis.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• sputum analysis
sputum analysis to diagnose tuberculosis
• lymph node biobsy
to diagnose tuberculous lymphadenitis

Locations
Country Name City State
Egypt Sohag university Hospital Sohag

Sponsors (1)
Lead Sponsor Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

References & Publications (4)

Ali MK, Karanja S, Karama M. Factors associated with tuberculosis treatment outcomes among tuberculosis patients attending tuberculosis treatment centres in 2016-2017 in Mogadishu, Somalia. Pan Afr Med J. 2017 Nov 2;28:197. doi: 10.11604/pamj.2017.28.197.13439. eCollection 2017. — View Citation

Horton KC, MacPherson P, Houben RM, White RG, Corbett EL. Sex Differences in Tuberculosis Burden and Notifications in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis. PLoS Med. 2016 Sep 6;13(9):e1002119. doi: 10.1371/journal.pmed.1002119. eCollection 2016 Sep. — View Citation

Jalal TMT, Abdullah S, Wahab FA, Dir S, Naing NN. Prevalence and Factors Associated with Tuberculosis Treatment Success among TB/HIV Co-Infection in North-East Malaysia. Malays J Med Sci. 2017 Dec;24(6):75-82. doi: 10.21315/mjms2017.24.6.9. Epub 2017 Dec 29. — View Citation

Mason PH, Snow K, Asugeni R, Massey PD, Viney K. Tuberculosis and gender in the Asia-Pacific region. Aust N Z J Public Health. 2017 Jun;41(3):227-229. doi: 10.1111/1753-6405.12619. Epub 2016 Dec 13. No abstract available. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary percent of cured tuberculous patients to detect percent of cured patients 1 year
Primary percent of treatment failure to detect percent of treatment failure in tuberculous patients 1 year
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