Trigeminal Neuralgia Clinical Trial
Official title:
Prognosis of Trigeminal Neuralgia When Enrolled in a Multidisciplinary Management Program - a Two-year Prospective Real-life Study
Background: Prognosis of medically treated trigeminal neuralgia patients is assumed to be
poor, but the evidence is lacking. Thus, prospective real-life studies of medical management
of trigeminal neuralgia are warranted.
Methods: Observational study. Patients were consecutively enrolled in a structured management
program at a specialist centre for facial pain. Optimisation of medical treatment,
physiotherapy, psychotherapy, and advice from trained nurses, were parts of the program.
Medically intractable patients were referred for neurosurgery. Data-collection was
prospective using standardised schemes and patient surveys. The aim was to describe the
two-year outcome of medical treatment at the specialist centre. The primary outcome was a 50%
reduction in the overall burden of pain according to a Numerical Rating Scale (NRS) after two
years.
This study aimed to provide evidence concerning the real-life efficacy of medical management
of trigeminal neuralgia (TN) when directed by specialists. The investigatgors hypothesised
that the two-year prognosis in a group of medically managed TN patients enrolled in a
structured multidisciplinary management program was favourable, defined as a 50 % reduction
of the overall burden of pain over a two-year period
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05152368 -
Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Trigeminal Neuralgia and Peripheral Neuropathy
|
Phase 1 | |
| Recruiting |
NCT02801630 -
An Evaluation of the Effect of a Surface Acoustic Wave Patch Device on the Symptons of Trigeminal Neuralgia
|
N/A | |
| Completed |
NCT02473016 -
Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia
|
Phase 2 | |
| Recruiting |
NCT01364259 -
A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia
|
Phase 3 | |
| Completed |
NCT01364272 -
Diffusion Tensor Imaging Magnetic Resonance Imaging (DTI MRI) as a Correlate to Pain Relief and Facial Numbness in Patients Following Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia
|
||
| Completed |
NCT00603694 -
Hippocampal Radiation Exposure and Memory
|
N/A | |
| Completed |
NCT00913107 -
Efficacy and Safety Study of Lamotrigine to Treat Trigeminal Neuralgia
|
Phase 2/Phase 3 | |
| Recruiting |
NCT04996199 -
Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial
|
Phase 4 | |
| Completed |
NCT06240494 -
Predictive Factors in Maxillary and Mandibular Nerve Radiofrequency Treatment for Trigeminal Neuralgia
|
||
| Completed |
NCT05712993 -
Comparative Study Between Transcoronoid and Infrazygomatic Anterior Maneuvers
|
N/A | |
| Completed |
NCT04371575 -
Symptomatic Trigeminal Neuralgia Attributed to Multiple Sclerosis - a Prospective Study in 60 Patients
|
||
| Completed |
NCT03669744 -
Regional Anesthesia in Refractory Trigeminal Neuralgia: 21 Cases Reported to the Limoges University Hospital
|
||
| Completed |
NCT05032573 -
Feasibility of Olive Oil for Reducing Facial Pain of Trigeminal Neuralgia
|
N/A | |
| Recruiting |
NCT05615714 -
Paresthesia-free Peripheral Nerve Field Stimulation for Trigeminal Neuralgia (FreeST Trial)
|
Phase 1/Phase 2 | |
| Recruiting |
NCT04054024 -
Efficacy and Tolerability of Erenumab in Patients With Trigeminal Neuralgia
|
Phase 2 | |
| Not yet recruiting |
NCT05451251 -
Deep Brain Stimulation for Refractory Trigeminal Neuralgia With a Demyelinating Pontine Lesion
|
N/A | |
| Withdrawn |
NCT04353505 -
Intra-arterial Sphenopalatine Ganglion Block for Patients With Refractory Headache
|
Phase 1 | |
| Withdrawn |
NCT01932255 -
CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap
|
N/A | |
| Completed |
NCT05075707 -
Comparison Between Magnetic Field and Laser Therapy in Management of Trigeminal Neuralgia
|
N/A | |
| Completed |
NCT06334796 -
Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology
|
Early Phase 1 |