Trigeminal Neuralgia Clinical Trial
Official title:
Hippocampal Radiation Exposure and Memory: A Pilot Study
Neurocognitive impairment as a result of gamma knife radiosurgery has not been well studied
and is poorly understood. Radiosurgery to the base of skull for the treatment of benign and
malignant disorders may consequently impair memory function. There is a need to evaluate
changes in memory function that may be associated with such exposures.
In this pilot study, we will investigate changes in hippocampal-dependent memory function in
10 patients receiving a low SRS dose to the hippocampus. We will also investigate such
changes in a no-dose control group and a high-dose control group. This study will provide
preliminary estimates of variance in memory changes associated with radiation exposure, and
will then permit us to design future studies with the appropriate sample size justification.
n/a
Observational Model: Case Control, Time Perspective: Prospective
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