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Treatment clinical trials

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NCT ID: NCT05748561 Recruiting - Treatment Clinical Trials

Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.

Start date: April 5, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this double-blind prospective randomized clinical trial is to determine if the effect of intravenous erythropoietin is superior to the effect of intravenous methylprednisolone in cases of toxic optic neuropathy 4 weeks after therapeutic intervention. The main question it aims to answer: • Is there a difference in the visual recovery of toxic optic neuropathies treated with intravenous methylprednisolone in comparison with those treated with intravenous erythropoietin?

NCT ID: NCT05743933 Not yet recruiting - Treatment Clinical Trials

Cohort Study of Adrenogenic Autonomic Cortisol Secretion

Start date: February 17, 2023
Phase:
Study type: Observational

To investige the etiology, pathogenesis, diagnosis and treatment of adrenogenic autonomic cortisol secretion in Chinese adults.

NCT ID: NCT05731102 Completed - Clinical trials for Substance Use Disorders

Diagnostic Survey of Mental and Substance Use Disorders Among Norwegian College and University Students

Start date: January 24, 2023
Phase:
Study type: Observational

The aims of this observational survey are to 1) collect data on the prevalence of mental and substance use disorders, and 2) investigate risk factors and consequences of mental and substance use disorder

NCT ID: NCT05713175 Completed - Orthopedic Disorder Clinical Trials

Orthopaedic Treatment in Propulsive Metatarsalgia

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effectiveness of two conservative orthopedic treatments in propulsive metatarsalgia. The main question it aims to answer are: - To compare the effectiveness of treatments on foot pain and functionality in subjects diagnosed with propulsive metatarsalgia. - To determinate the influence of clinical and radiographical characteristics in pain improvement. Participants will wear the treatment for 3 months . Researchers will compare polypropylene and EVA insoles and Fixtoe Device® to see if a foot pain improvement is achieved.

NCT ID: NCT05694767 Recruiting - Clinical trials for Immune Thrombocytopenia

A Prospective, One-arm and Open Clinical Study of CM313 in the Treatment of Immune Thrombocytopenia

2022-CM313-ITP
Start date: January 22, 2023
Phase: Phase 2
Study type: Interventional

To evaluate the safety and efficacy of CM313 in the treatment of immune thrombocytopenia in patients who have not responded adequately or relapsed after first-line treatment and at least one second-line therapy including rituximab and/or TPO-RA.

NCT ID: NCT05617417 Completed - Clinical trials for Urinary Incontinence

The Efficacy of Injectable Platelet-rich Fibrin in the Treatment of the Female Stress Urinary Incontinence

Start date: May 5, 2021
Phase: N/A
Study type: Interventional

We aimed to evaluate the efficacy of locally applied injectable platelet-rich fibrin in women with stress urinary incontinence. We searched whether there was a decrease in the severity of urinary incontinence after the injection of platelet-rich fibrin. The participants will answer questionnaires about urinary incontinence before and after the injectable platelet-rich fibrin treatment.

NCT ID: NCT05573867 Recruiting - Treatment Clinical Trials

Digital Coaching With" Physical Activity on Prescription ( FaR) to Increase Physical Activity and Reduce Post Stroke Fatigue

Start date: June 12, 2023
Phase: N/A
Study type: Interventional

Stroke is the leading cause in the world considering disabilities and approximately half of the patient population experience post stroke fatigue (PSF). PSF affects the patients level of activity and their quality of life. Even patients with mild stroke claim that PSF is one of the main reasons hindering them from being physically active. People suffering from stroke generally have lower physical capacity compared to healthy individuals of the same age and they are spending more time in sedentary. Physical inactivity is considered to be one of the main modifiable risk factors for stroke. There is strong evidence that physical activity will improve health and reduce the risk of future strokes. Evaluation of interventions to reduce PSF is a prioritized research field since it is currently lacking evidence. There is a possibility that physical training can have a positive effect on PSF. Digital alternatives to on-site visits will increase the availability and can strengthen the patients independence which is according to the government and Sveriges Kommuner och Regioner ( SKR) common vision for e-health. The aim of this study is to evaluate the feasibility of individualized, digital coaching twice a week for 12 weeks with "Physical activity on prescription" (FaR) to increase physical activity and reduce PSF after stroke.

NCT ID: NCT05540119 Recruiting - Gastric Cancer Clinical Trials

Swedish Oesophago-Gastric Study

SOEGAS
Start date: May 1, 2017
Phase:
Study type: Observational

The overarching aim of this nationwide Swedish cohort study is to reduce death and suffering from oesophageal and gastric tumours. This aim can be accomplished by a broad research approach that aims to identify: 1. Risk factors and preventive actions 2. Early detection 3. Improved treatment

NCT ID: NCT05537155 Not yet recruiting - Clinical trials for Postoperative Delirium

Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery

Start date: October 2022
Phase: N/A
Study type: Interventional

This study is designed to test the hypothesis that, for older orthopedic patients who developed postoperative delirium, combining buccal acupuncture with routine care will shorten delirium duration and relieve delirium severity.

NCT ID: NCT05461820 Recruiting - Treatment Clinical Trials

Effects of Different Treatment Schemes on the Regulation and Recurrence of Graves' Disease

Start date: May 1, 2018
Phase: Phase 4
Study type: Interventional

In this study, the dose of methimazole was adjusted according to the different states of thyroid function, and the effects of conventional therapy and intensive therapy on the cumulative recurrence of Graves' hyperthyroidism after two years of drug withdrawal were evaluated. At the same time, the changes of immune indexes and inflammatory factors in the regulation process were evaluated. This study is a phase IV clinical study designed and carried out by the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), which is a randomized, open and routine treatment group with parallel control.