Traumatic Brain Injury Clinical Trial
Official title:
Neuroimaging & Plasma Markers for Predicting Outcomes After Mild Traumatic Brain Injury
This exploratory study aims to identify the most promising biomarkers that alone or in combination might predict development of mood disorders [i.e., major depression (MD], cognitive disorders [i.e., executive function deficits (EFD)], and functional impairment following repetitive/mild traumatic brain injury (MTBI).
This will be a prospective study of subjects with MTBI, body injury and healthy controls.
Subjects who meet the study criteria will be enrolled in the study after they provide
informed consent.
All subjects will be followed longitudinally at 3 and 6 months post-injury.
All subjects will have 3-4 visits:
Screening visit to determine eligibility; first study visit within 1 month of injury for
those with brain or body injury (at the time of screening or within 1 month of screening for
healthy controls); second study visit at 3 months post-injury (3 months after the first
visit for healthy controls) and third study visit at 6 months post-injury (6 months after
the first visit for healthy controls).
;
Observational Model: Case Control, Time Perspective: Prospective
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