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Transplant; Failure, Liver clinical trials

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NCT ID: NCT03723304 Completed - Liver Cancer Clinical Trials

The Intention-to-treat Effect of Bridge Therapies in the Setting of Milan-in Patients

Start date: March 1, 2018
Phase:
Study type: Observational

In patients with hepatocellular cancer (HCC) meeting the Milan Criteria (MC), the usefulness of loco-regional therapies (LRT) in the context of liver transplantation (LT) is still debated. The inconsistent literature data are the result of initial selection biases among treated and untreated patients. In order to overcome these shortcomings, an inverse probability of treatment weighting (IPTW) analysis was done in a large patient cohort. After using a competing-risk analysis, the primary end-point of the study aims at identifying the risk factors of HCC-specific LT failure, defined as pre-LT tumour-related drop-out or post-LT recurrence.

NCT ID: NCT03647059 Not yet recruiting - Clinical trials for Transplant; Failure, Liver

Rapid Assessment of Donor Liver Quality

Start date: August 15, 2018
Phase:
Study type: Observational [Patient Registry]

Aims: 1. Conduct multi-center, prospective and open research on liver quality assessment and establish LSCM liver quality assessment system 2. Classification of liver quality grades by LSCM for different pathological conditions (steatosis, fibrosis, hepatocyte necrosis, etc.) 3. Compare the specificity and sensitivity of LSCM evaluation results with the results of liver donor quality evaluation and intraoperative pathological biopsy results. 4. LSCM classifies the quality of donor liver and compares the recovery of liver function on the first day after liver transplantation. 5. LSCM grades the quality of donor liver and compares the long-term prognosis

NCT ID: NCT03310905 Recruiting - Clinical trials for Transplant;Failure,Kidney

Abdominal Wall Transplant

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects. Abdominal wall transplantation may be performed alone or in combination with another transplant.

NCT ID: NCT03265249 Terminated - Pain, Postoperative Clinical Trials

BRIDGE Device for Post-operative Pain Control

BRIDGE
Start date: February 12, 2018
Phase: N/A
Study type: Interventional

Auricular neurostimulation is a potential novel and non-invasive method of pain control following liver transplantation in a growing patient population with the probability of significant impact on economics and morbidity. The investigators propose a pilot study to investigate the effects of auricular neurostimulation in patients receiving a liver transplantation. The investigator will investigate the effects of auricular neurostimulation with this novel device and compare it to the current standard of care for pain management following liver transplantation.