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Efficacy Study of Clopidogrel in High-risk Population With Acute Non-disabling Cerebrovascular Events Ⅱ

Transient Ischemic Attack Clinical Trial

Official title:
Multicentre, Double-blind, Double-simulation, Randomized Controlled Clinical Trial of Ticagrelor/Aspirin Versus Clopidogrel/Aspirin for the Prevention of Stroke in a Population at High Risk for Non-crippling Cerebrovascular Events Carrying the CYP2C19 LOF Allele

Clinical Trial Summary

The purpose of this study was to test whether ticagrelor combined with aspirin can reduce the recurrence rate of stroke within 3 months compared with clopidogrel combined with aspirin in patients at high risk of non-disablement ischemic cerebrovascular events who carry the CYP2C19 function loss allele within 24 hours of onset.

Clinical Trial Description

This study was a multicenter, double-blind, double-simulated, randomized controlled study. To test whether ticagrelor combined with aspirin reduces the recurrence rate of stroke within 3 months compared with clopidogrel combined with aspirin in patients with a high risk of noncrippling ischemic cerebrovascular events with CYP2C19 loss within 24 hours of onset. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04952311
Study type Interventional
Source Peking University Third Hospital
Contact Yu Fu
Phone +86 15611908699
Email lilac_fu@sina.com
Status Recruiting
Phase Phase 3
Start date June 1, 2019
Completion date September 30, 2021
View Details
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