Clinical Trials Logo
  1. Home
  2. Transient Ischemic Attack
  3. NCT04952311

Efficacy Study of Clopidogrel in High-risk Population With Acute Non-disabling Cerebrovascular Events Ⅱ

Transient Ischemic Attack Clinical Trial

Official title:
Multicentre, Double-blind, Double-simulation, Randomized Controlled Clinical Trial of Ticagrelor/Aspirin Versus Clopidogrel/Aspirin for the Prevention of Stroke in a Population at High Risk for Non-crippling Cerebrovascular Events Carrying the CYP2C19 LOF Allele

Clinical Trial Summary

The purpose of this study was to test whether ticagrelor combined with aspirin can reduce the recurrence rate of stroke within 3 months compared with clopidogrel combined with aspirin in patients at high risk of non-disablement ischemic cerebrovascular events who carry the CYP2C19 function loss allele within 24 hours of onset.

Clinical Trial Description

This study was a multicenter, double-blind, double-simulated, randomized controlled study. To test whether ticagrelor combined with aspirin reduces the recurrence rate of stroke within 3 months compared with clopidogrel combined with aspirin in patients with a high risk of noncrippling ischemic cerebrovascular events with CYP2C19 loss within 24 hours of onset. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04952311
Study type Interventional
Source Peking University Third Hospital
Contact Yu Fu
Phone +86 15611908699
Email lilac_fu@sina.com
Status Recruiting
Phase Phase 3
Start date June 1, 2019
Completion date September 30, 2021
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT00859885 - International PFO Consortium N/A
Not yet recruiting NCT03605355 - Feasibility Study on the Medical and Economic Consequences of Outpatient Management of TIAs and Minor Strokes
Completed NCT03281590 - Stroke and Cerebrovascular Diseases Registry
Completed NCT02905383 - The Effect of Exercise on Physical Function and Health in Older People After Discharge From Hospital N/A
Completed NCT04078737 - Clopidogrel With Aspirin in High-risk Patients With Acute Non-disabling Cerebrovascular Events II Phase 3
Completed NCT02141932 - Pocket-size Cardiovascular Ultrasound in Stroke N/A
Recruiting NCT01954329 - Markers in the Diagnosis of TIA N/A
Completed NCT02011256 - Early Detection Of Atrial Fibrillation In Patients With Transient Ischemic Attack N/A
Completed NCT01918891 - Center for Stroke Disparities Solution - Community Transitions Intervention N/A
Recruiting NCT01526824 - Lovaza's Effect on Clopidogrel in a Neuro Population Phase 0
Completed NCT01020851 - The PREVENTS Trial: The Preventing Recurrent Events in Veterans Navigating Transient Ischemic Attack (TIA) or Stroke Trial N/A
Completed NCT00597974 - Neurological Outcome With Carotid Artery Stenting N/A
Completed NCT00211731 - Preventing Recurrent Stroke in Minority Populations N/A
Active, not recruiting NCT03635749 - Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis Phase 3
Completed NCT03153020 - Determinants of Adherence to Post-stroke/Transient Ischemic Attack Secondary Prevention Treatment: Cohort Study in the Rhône
Recruiting NCT04075500 - Optimal Detection of Atrial Fibrillation in TIA N/A
Recruiting NCT06091319 - Florbetaben for Imaging of Vascular Amyloid
Completed NCT04604015 - RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt N/A
Completed NCT00885456 - Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT Phase 2
Completed NCT05620966 - EEG to Diagnose TIA and Stroke