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Transgenderism clinical trials

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NCT ID: NCT06221163 Not yet recruiting - Transgenderism Clinical Trials

Sociological Study of the Life Courses of Young TRANSgender Patients

ParTransRep
Start date: April 2024
Phase:
Study type: Observational

The number of people consulting for a request related to trans identity is increasing sharply. The study monocentric qualitative study of discursive material aims to describe the diversity of practices and discourses mobilized by the people concerned and their relatives in the wake of work already carried out in the human sciences. Conducting non-directive interviews (life stories) with transgender patients consulting the Reproductive Medicine Department and their volunteer relatives.The ceiling is 20 interviews and 80 hours of observation.

NCT ID: NCT06218446 Not yet recruiting - Fertility Issues Clinical Trials

Transgender Caregivers' and Patients' Representations of Parenthood as Part of a Fertility Preservation Pathway

TransFert
Start date: February 2024
Phase:
Study type: Observational

This research aims to understand the impact of fertility preservation consultation on transgender patients' projection and how the possibility of preserving gametes influences transgender people's transition paths, parenthood projects and health and health of transgender people through qualitative interviews. This research will also study the representations of members of medical and reproductive biology teams the possible use of stored gametes, and how these representations influence their clinical practice. clinical practice. To answer the research question, we plan to include 30 patients who have consulted for fertility preservation at the at the CECOS of the Tenon hospital, located in the 20th arrondissement of Paris, and 20 members of the center's healthcare team. care team.

NCT ID: NCT06149065 Completed - Acne Clinical Trials

Factors Associated With the Acne Severity Among Transmen Population: a Cross-sectional Study

Start date: June 5, 2021
Phase:
Study type: Observational [Patient Registry]

The goal of this observational cross-sectional study is to identify factors associated with severity of acne in Thai transmen receiving masculinizing hormone therapy. The main questions it aims to answer are: - What are the factors associated with severity of acne in transmen? - Does masculinizing hormone therapy associate with the severity of acne in transmen? Participants will be asked to complete an online questionnaire and allow to take pictures of their face for acne assessment purpose.

NCT ID: NCT06093724 Recruiting - Transgenderism Clinical Trials

Prospective Imaging Assessment of Perineo-pelvic Static's Evolution After Sexual Reassignment Surgery in MtF Transgender Patient, by Peno-scrotal Inversion Vaginoplasty Technique (TRANSPELV)

TRANSPELV
Start date: August 21, 2023
Phase: N/A
Study type: Interventional

The research consists of adding to the usual MtF transgender patient undergoing vaginoplasty care course, static and dynamic perineo-pelvic MRI before, and at 6 and 24 months. The aim is to assess perineo-pelvic static's evolution, based on the appearance of a rectocele.

NCT ID: NCT06074796 Recruiting - Transgenderism Clinical Trials

The Determinants of Fertility Preservation in TRANSgender Patients.

FP-TRANS
Start date: September 25, 2023
Phase:
Study type: Observational

The study is monocentric, retrospective, non-interventional and does not involve human subjects. The main objective is to compare the profiles of transgender patients who undergo fertility preservation with those who do not. The secondary objectives are to define the rate of recourse to fertility preservation, determine the proportion of patients wishing to become parents. Statistical analysis will be carried out with a view to highlighting significant determinants in transgender patients by comparing those who undergo fertility preservation with those who do not. The data will have been collected during routine consultations as part of the transition process for transgender patients. This is taking place in the reproductive medicine department of the regional university hospital centre in Nancy.

NCT ID: NCT06070324 Not yet recruiting - Breast Cancer Clinical Trials

Effect of Suture Material on Postoperative Nipple Areolar Complex Widening

Start date: December 2023
Phase: N/A
Study type: Interventional

This will be a single-blinded study where participants are blinded to the suture type but the surgeon will draw a random, unmarked envelope containing the designated suture type at the start of the surgery. The patient population will be all patients undergoing breast surgery at the London Health Sciences Center (LHSC) - ie. University Hospital, Victoria Hospital and the Nazem Kadri Surgical Center, and St. Joseph's Hospital. Three (3) main procedure groups will be transgender gender-affirming top surgery, cisgender female breast reduction or augmentation (including healthy and cancer patients; subgroup analysis will be performed), and cisgender male gynecomastia surgery. The goal is n=180 patients, n=60 per type of suture with n=20 per type of procedure (totaling n=60 per type of procedure). NAC width for each breast will be measured intraoperatively, at 2 weeks postop, 6 weeks postop, 3 months postop, and 6 months postop. These measurements will be deidentified and logged into a secure data entry form. Information on whether a secondary outcome occurred (ie. infection, dehiscence, revision and nipple necrosis) will be logged in this form as well. Because the sutures will be kept non-visible under dressings until the clinical followup appointment 2 weeks postop, the patient will remain blinded as to the type of suture used on their NAC(s). At this point, absorbable sutures will have been largely dissolved and non-absorbable sutures will be removed.

NCT ID: NCT05883553 Recruiting - Clinical trials for Erectile Dysfunction

Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.

EROS
Start date: May 17, 2023
Phase: N/A
Study type: Interventional

Transgender and gender diverse (TGD) individuals most often choose for phalloplasty as a means to create masculine external genitalia. The neophallus created in phalloplasty is usually insufficient for penetrative sexual intercourse due to the lack of erectile structures. Therefore, implantation of an internal erectile prosthesis or use of an external device or epithesis is required. Internal prostheses are the main method for attaining penile rigidity after phalloplasty, but they carry a high risk of complications. Previous research has shown that up to 22% of prostheses for cisgender men were explanted due to various reasons, including infection, erosion, and malfunction within 20 months. The lack of reliable and durable erectile devices leads to a large proportion of patients either choosing phalloplasty but never going for the placement of an erectile prosthesis or completely abandoning the idea of GGAS under the form of phalloplasty. Secondarily, TGD individuals may be concerned about complication rates and likely need for additional surgeries associated with penile implant surgery. Therefore, alternative options for transgender and gender non-conforming patients after phalloplasty are needed. These alternatives may be surgical or non-surgical. External penile epitheses or penile splints were originally designed for cisgender men with erectile dysfunction but have been used experimentally by post-phalloplasty transgender men. While there is no data on the usability and durability of penile epitheses in a TGD population, they may be a viable alternative to an internal penile prosthesis after phalloplasty. Penile lifters or splints, marketed as ElatorTM or ErektorTM, are commercially available and consist of two rigid rings connected by rigid metal rods. The biggest of two rings is placed around the base of the phallus, and the second ring is placed behind the coronal ridge. By connecting the rods to the ring at the base of the penis, tension and rigidity between the two rings is created, allowing the user to penetrate their partner and remove the device after intercourse. The current study aims to extend the knowledge on these external devices by comparing them to the implantation of an internal penile prosthesis in post-phalloplasty transgender patients.

NCT ID: NCT05761678 Recruiting - Transgenderism Clinical Trials

Quality of Life of Transgender People - Implementation and Monitoring of an Online Cohort (e-QoL-Trans)

e-QoL-Trans
Start date: February 21, 2023
Phase:
Study type: Observational

Transgender people have an identity or an expression gender that differs from the sex assigned to them at the birth. Transgender people and their needs remain misunderstood, and more generally by society. THE transgender populations express poor quality of life compared to the general population. However, very few of studies are interested in these people, in their diversity of paths, trajectories and characteristics of life. More of research is needed to study the quality of life, understand the experiences, in their diversity and in the health, social and life trajectories. Researches must be carried out, in particular on how to interrogate by the seeks out transgender people, in order to prevent stigmatization within population studies. The main objective of this study is to assess the quality of life of people transgender people during their life trajectory and their transition path, based on validated questionnaires scientifically in French, for major themes of the population concerned (quality of life, social support perceived).

NCT ID: NCT05728853 Completed - Transgenderism Clinical Trials

Is Bioimpedance Analysis Accurate in Transgender Males?

Start date: April 20, 2023
Phase:
Study type: Observational

Accurate fat mass and muscle mass assessment is an informative marker of an individual's health. However, the optimal method for assessing body composition in transgender males remains to be determined. Here, the investigators aim to compare body composition estimates in transgender males by bioimpedance analysis using the reference settings for males and females and by

NCT ID: NCT05666102 Completed - HIV Infections Clinical Trials

Transgender Men's Perspectives on HIV Risk and HIV Prevention Interventions

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The goal of this pilot study is to gather and analyze qualitative data from focus groups with Transgender men who have sex with men (TMSM) to learn more about the life experiences unique to TMSM that influence their attitudes and beliefs about HIV risk, as well as to better understand the intersections of these specific sexual and gender identities.