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Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVR

Transcatheter Aortic Valve Replacement Clinical Trial

Official title:
Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVR

Clinical Trial Summary

This is a multicenter, open-label, randomized controlled study meant to test the superior efficacy of oral anticoagulation (OAC) therapy versus single antiplatelet therapy (SAPT) in patients after TAVR. Patients who accept successful TAVR will be randomized to receive either the OAC group (Vitamin-K antagonists) or the SAPT group (aspirin) for 6 months on a 1:1 ratio. After that, patients from both groups will be treated with single antiplatelet therapy (aspirin). All patients will be followed for 1 year to test the difference between net clinical benefits and bioprosthetic valve thrombosis diagnosed by 4D-CT.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05375474
Study type Interventional
Source China National Center for Cardiovascular Diseases
Contact Yongjian Wu, MD,PhD
Phone +86 13701387189
Email yongjianwu_nccd@163.com
Status Recruiting
Phase Phase 4
Start date July 27, 2023
Completion date December 31, 2025
View Details
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