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Total Knee Arthroplasty clinical trials

View clinical trials related to Total Knee Arthroplasty.

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NCT ID: NCT05138406 Recruiting - Clinical trials for Total Knee Arthroplasty

Graded Motor Imagery and Total Knee Arthroplasty

Start date: February 28, 2022
Phase: N/A
Study type: Interventional

This study was planned to investigate the long-term effectiveness of the early application of graded motor imagery therapy on pain parameters, functional performance, motor imagery skill, and kinesiophobia in individuals who underwent total knee arthroplasty surgery after knee osteoarthritis.

NCT ID: NCT05137080 Completed - Clinical trials for Total Knee Arthroplasty

Dexamethasone and Functional Outcome After TKA

Start date: December 15, 2021
Phase: Phase 4
Study type: Interventional

Patients previously included in the DEX-2-TKA-trial (ethics committee ID SJ-695; ClinicalTrials.gov: NCT03506789) at Næstved Hospital will be invited for a follow up study consisting of questionnaires and a visit with a physical therapist. The study includes the following validated questionnaires: EQ-5D-5L, Oxford Knee Score and PainDetect, and information on height, weight, daily pain-medication and co-morbidities. With the physical therapist, the patient will perform the following functional tests: knee range of motion, timed-up-to-go, 30 second chair stand test, 40m fast paced walk test, stair climb test and a measure of the thigh force.

NCT ID: NCT05132595 Recruiting - Postoperative Pain Clinical Trials

Esketamine vs. Ketorolac for Prevention of Postoperative Pain and Cognitive Dysfunction After Total Knee Arthroplasty

Start date: November 30, 2021
Phase: N/A
Study type: Interventional

Purpose: To compare esketamine and ketorolac separately and in combination to prevent postoperative pain and cognitive dysfunction after total knee arthroplasty

NCT ID: NCT05130216 Enrolling by invitation - Clinical trials for Total Knee Arthroplasty

Genicular Nerve Radiofrequency Ablation for Chronic Knee Pain After Total Knee Arthroplasty

Start date: September 22, 2021
Phase:
Study type: Observational

Determine if genicular nerve radiofrequency ablation (RFA) is a clinically effective intervention for patients with chronic knee pain post-total knee arthroplasty (TKA) as defined by pain.

NCT ID: NCT05119764 Completed - Knee Osteoarthritis Clinical Trials

Manual Lymphatic Drainage Before and After Total Knee Replacement, a Single-center Observer-blinded Randomized Controlled Trial

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The aim of this observer-blinded randomized controlled trial is the evaluation of the influence of manual lymphatic drainage (MLD) on the outcome of patients receiving total knee replacement (TKA).

NCT ID: NCT05113901 Terminated - Clinical trials for Total Knee Arthroplasty

Medrol Dosepak Taper for Delayed Post-op Recovery After TKA

Start date: March 3, 2022
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy of a methylprednisolone taper on patients with decreased range of motion (ROM) or delayed recovery in the acute postoperative period following total knee arthroplasty (TKA). Patients with decreased ROM or delayed recovery six weeks to three months post-TKA will improve ROM and patient-reported outcomes at two weeks post-treatment initiation of methylprednisolone taper, as compared to similar patients who receive a placebo taper.

NCT ID: NCT05107414 Recruiting - Clinical trials for Total Knee Arthroplasty

Journey 2 Multi Center Kinematic Study

Start date: May 15, 2021
Phase:
Study type: Observational

The objective of this study is to determine and compare the in vivo kinematics and vibroarthrography (VAG) signals for subjects implanted with Journey II Bi-Cruciate Stabilized (BCS), CR (Cruciate Retaining), and Bi-Cruciate Retaining (XR) TKAs.

NCT ID: NCT05097976 Recruiting - Clinical trials for Total Knee Arthroplasty

Medrol Dosepak for Outpatient Total Knee Arthroplasty

Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy of an oral methylprednisolone taper on acute postoperative pain, function, opioid consumption, nausea, and complications following outpatient total knee arthroplasty (TKA). We hypothesize that administration of an oral methylprednisolone taper starting on postoperative day 1 (POD 1) following TKA will be associated with improved pain and decreased opioid use, nausea, and complications at POD1-7, as compared to similar patients who receive placebo. Additionally, those taking methylprednisolone will report decreased pain and greater objective functional outcomes at 3 and 6 weeks postoperatively as compared to controls.

NCT ID: NCT05088551 Completed - Clinical trials for Total Knee Arthroplasty

The Effect of the Educational Plan Prepared According to the Health Literacy Levels of Patients

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The reasons such as the advanced age of most patients with Total Knee Arthroplasty (TKA), the presence of concomitant diseases, and bilateral prostheses cause a decrease in the quality of life by negatively affecting the healing processes of the patients. Patients who try to adapt to the problems experienced during postoperative recovery need the information to develop coping behaviors. Nurses play a crucial role in ensuring adequate and effective access of information to the patient during this challenging process, which significantly affects mobility and, consequently, life activities. Effective educational interventions to be implemented by nurses enable patients to make decisions about health problems and act to improve their quality of life. However, for patient education to be efficient, the information given must be easy to read, understandable, and suitable for various learning styles to cope with problems more effectively. Still, individuals with low health literacy have problems benefiting from all services provided, exceptionally patient education, at the desired level.

NCT ID: NCT05086393 Recruiting - Pain, Postoperative Clinical Trials

Duloxetine RCT on Postop TKA Outcomes

Start date: November 1, 2021
Phase: Phase 4
Study type: Interventional

The aim of this study is to determine if duloxetine is associated with differences in post-operative pain, patient-reported outcome measures, and opioid consumption in patients undergoing primary total knee arthroplasty compared to patients who do not receive the medication. If so, duloxetine has the potential to become widely incorporated into the multi-modal analgesic regimen given to patients following knee replacements.