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Toothache clinical trials

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NCT ID: NCT02463552 Completed - Tooth Bleaching Clinical Trials

Naproxen on Tooth Sensitivity Caused by In-office Bleaching

Start date: May 2015
Phase: N/A
Study type: Interventional

This study aims to evaluate the effects of prior use of non-steroidal anti-inflammatory Naproxen on risk and level of tooth sensitivity caused by in-office bleaching procedures.

NCT ID: NCT02443207 Completed - Dental Caries Clinical Trials

Impact of Dental Pain on the Quality of Life

Start date: January 2013
Phase: N/A
Study type: Observational [Patient Registry]

The aim of the present study was to evaluate the perceived impact of dental caries and dental pain on oral health-related quality of life (OHRQoL) among preschool children and their families. A cross-sectional study was conduct with 843 preschool children in Campina Grande, Brazil. Parents/caregivers answered a questionnaire on socio-demographic information, their child's general/oral health and history of dental pain. The Brazilian version of the Early Childhood Oral Health Impact Scale was administered to determine the perceived impact of caries and dental pain on OHRQoL. Children have undergone an oral examination. Logistic regression for complex sample was used to determine associations between the dependent and independent variables (OR: odds ratio; α = 5%).

NCT ID: NCT02320708 Completed - Dental Pain Clinical Trials

Study of Acetaminophen (ACE) in Post-operative Dental Pain

Start date: December 31, 2014
Phase: Phase 2
Study type: Interventional

This is a dental pain study evaluating the efficacy and safety of a single dose of test acetaminophen (ACE) (1000 mg) compared to commercial acetaminophen (1000 mg), ibuprofen (IBU) (400 mg), and placebo over a 6 hour period. Subjects will undergo dental extraction of three or four third molars.

NCT ID: NCT02209181 Completed - Pain Clinical Trials

A Dental Pain Study to Test the Effectiveness of a New Pain Reliever Medicine

Start date: August 2014
Phase: Phase 2
Study type: Interventional

To assess the safety and effectiveness one dose of a new pain reliever medicine (JNJ-10450232 at either the 250 or 1000 mg strength) compared with placebo (sugar pill) or acetaminophen 1000 mg after surgical removal of third molars. The primary endpoint will evaluate pain relief effectiveness up to 6 hours after administration of the study drug.

NCT ID: NCT02084511 Completed - Pain, Postoperative Clinical Trials

Effectiveness and Safety of Different Doses of BI 1026706 in Patients With Postoperative Dental Pain

Start date: March 2014
Phase: Phase 1
Study type: Interventional

To investigate the effectiveness of BI 1026706 powder for reconstitution of an oral solution compared to placebo and the relative effectiveness compared to Celecoxib.

NCT ID: NCT01960114 Completed - Dental Pain Clinical Trials

Study of Long-Acting Acetaminophen in Postoperative Dental Pain

Start date: October 2013
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of acetaminophen ER 1500 mg (two 750 mg tablets) over 10 to 12 hours in the dental pain model following third molar extraction(s) and to evaluate the pharmacokinetics of acetaminophen ER 1500 mg (two 750 mg tablets) in a sub-group of subjects.

NCT ID: NCT01920386 Completed - Clinical trials for Acute Toothache Patients Above Moderate Pain After Teeth Extraction Surgery

Phase 3 Study of Tramadol Hydrochloride/Acetaminophen SR Tab. & Tramadol Hydrochloride/Acetaminophen Tab. in Acute Toothache Patients After Teeth Extraction Surgery

Start date: June 2013
Phase: Phase 3
Study type: Interventional

A randomized, double-blind, active-controlled, parallel, multicenter Phase 3 study of Tramadol hydrochloride/Acetaminophen SR Tab. & Tramadol hydrochloride/Acetaminophen Tab. in Acute Toothache Patients above Moderate Pain after Teeth Extraction Surgery.

NCT ID: NCT01868776 Completed - Clinical trials for Irreversible Pulpitis (Toothache)

Effect of Buffered Numbing Solution on Patients With Toothaches

Start date: March 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of buffered lidocaine (a numbing solution) on the ability to numb patients with toothaches. Buffered anesthetic (numbing) solutions have shown promise in some medical and dental research. Patients presenting with toothaches will be given either a buffered numbing solution or a nonbuffered numbing solution. Neither the patient nor the operator will know which solution they will receive. Root canal treatment will be performed on the tooth and the ability of the buffered versus non-buffered numbing solutions will be compared.

NCT ID: NCT01746355 Completed - Clinical trials for Atypical Facial Pain or Atypical Odontalgia

Assessment and Treatment Patients With Atypical Facial Pain Trough Repetitive Transcranial Magnetic Stimulation

EMTr-AFP
Start date: March 2011
Phase: N/A
Study type: Interventional

Atypical Facial Pain is a chronic condition and presents controversies during diagnostic and treatment, between specialist not have consensus about the pathophysiology. It is possible consider this entitie a potential neuropathic cause without pathological signs. It knows the repetitive transcranial magnetic presents good results in the treatment of chronic pain coditions. The aim this study is evaluated the thresholds and excitability cortical in patients with AFP and verify the patterns of improvement in pain for patients undergoing rTMS compared to controls, as well as the therapeutic response to neuromodulation procedures. This enroll 20 patients with DAF and 20 controls treated with rTMS (5 sessions) and evaluated through questionnaires (EDOF clinical record, McGill Pain Questionnaire, Visual Analogue Scale, Inventory of symptoms of neuropathic pain, neuropathic pain DN4 questionnaire, SF -36, brief pain inventory). At the end of the data will be statistically analyzed and expressed as mean and standard deviation, and analyzed by Student's t test, analysis of variance (ANOVA), Tukey-Kramer and Pearson correlation. The level of significance is 5%. The results will be published in journals indexed in the area both nationally and internationally and presented at conferences and scientific meetings.

NCT ID: NCT01587950 Completed - Dental Pain Clinical Trials

The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity

Start date: February 2009
Phase: Phase 1
Study type: Interventional

A randomized, controlled, double blind exploratory study to explore the effects of two different potassium nitrate concentrations and water on exposed dentine in reducing dentinal hypersensitivity. Solutions will be applied for either 2, 5 or 10 minutes and assessed by visual analogue scale (VAS) scores following evaporative (air) stimulus.