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Tissue Adhesions clinical trials

View clinical trials related to Tissue Adhesions.

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NCT ID: NCT05415059 Not yet recruiting - Adhesion Clinical Trials

LEAFix Adhesion in Healthy Volunteers

Start date: August 10, 2022
Phase: N/A
Study type: Interventional

This study compares the adhesiveness of the 3M material to be used in the final design.

NCT ID: NCT05414760 Completed - Clinical trials for Intrauterine Adhesion

Evaluate Formation of IUAs After Third-generation Endometrial Ablation, With and Without Intrauterine Adhesion Barrier

CLEAN
Start date: November 11, 2022
Phase: N/A
Study type: Interventional

Evaluate the formation of adhesions after third-generation endometrial ablation, with and without the intrauterine adhesion barrier.

NCT ID: NCT05394662 Recruiting - Clinical trials for Intrauterine Adhesion

Safety and Effectiveness of Juveena™ Hydrogel System Following TCGP At High-Risk for Intrauterine Adhesions

Start date: August 11, 2022
Phase: Phase 3
Study type: Interventional

This study is to determine whether intrauterine instillation of Juveena hydrogel following adhesiogenic hysteroscopic procedures (TCGP + Juveena) can safely and effectively reduce the incidence and severity of intrauterine adhesions (IUA) compared to TCGP alone.

NCT ID: NCT05381376 Recruiting - Clinical trials for Intrauterine Adhesion

Multicentre Prospective Clinical Database for the Construction of Predictive Models on Risk of Intrauterine Adhesion

Start date: January 20, 2018
Phase:
Study type: Observational

1. To establish a follow-up database for uterine adhesions and a library of biological specimens for Intrauterine Adhesion. 2. using epidemiological surveys and biological analyses to screen risk factors for the development and prognosis of Intrauterine Adhesion. 3. Predictive models based on clinical and biochemical indicators, specimen testing and hysteroscopic images are also combined with statistical analysis and machine learning algorithms to enable patients' risk stratification and prognostic assessment.

NCT ID: NCT05376787 Not yet recruiting - Clinical trials for Adhesion of the Neutral Electrode 21pad

Medline NE Pad Adhesion Testing

Start date: May 16, 2022
Phase:
Study type: Observational

The purpose of this research study is to determine the neutral electrode 21pad adhesion to the skin in accordance with international standard IEC 60601-2-2 section 201.15.101.7. A neutral electrode is placed on the body of patients undergoing surgery that involves the use of electric current, to protect them from the harmful effects of the electricity.

NCT ID: NCT05360186 Recruiting - Clinical trials for First Trimester Abortion

New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCT

Start date: June 14, 2022
Phase: N/A
Study type: Interventional

The objective of this prospective, randomized controlled study was to evaluate the effectiveness of this NCH gel in the prevention of IUA development as assessed by hysteroscopy after USG-MVA, in the treatment for first-trimester miscarriage. - To study the severity and extent of the IUA as assessed by the AFS and ESGE adhesion score in both groups of patients. - To examine the rate of complications or side effects with the NCH gel. - To assess the subsequent menstrual history and reproductive outcome in both groups of patients.

NCT ID: NCT05265559 Recruiting - Adhesion Clinical Trials

Influence of Operator Factors on Succes and Survival of Indirect Restorations

Start date: October 9, 2018
Phase:
Study type: Observational [Patient Registry]

Background: Nowadays, tissue preserving, aesthetically high-quality and sustainable dentistry is more and more becoming the standard way of treatment. To reach those standards, one of the treatment options is applying a partial indirect restoration made by glass ceramics using immediate dental sealing (IDS). Using IDS, a protocol is followed to applicate a dentin bonding agent to freshly cut dentin when it is exposed during tooth preparation for indirect restorations (inlays/onlays, crowns). The preparation made for partial restorations is minimal invasive. Glass ceramic restorations have very high survival rates (90 to 100% after five years) (Morimoto et al., 2016) and glass ceramic mimics the color and structure of the tooth very well. This kind of treatment is gaining interest and increasingly applied however little information is available on the long-term effects when multiple general practitioners apply these restorations. Objectives: The main goal of this study is to evaluate partial posterior ceramic restorations with the application of an immediate dentin sealing (IDS) performed by various practitioners. Study design and population: Twenty dental practitioners, who followed a course on making ceramic partial restorations using IDS, will be asked to include patients for this study. The dental practitioners are being asked to share their data (occlusal light photo's, impression and x-rays) of twenty-five restorations they make after having the course. Restorations of individuals with a minimum age of 18 will be included. The information from pictures and impressions will be evaluated. Items to evaluate The practitioners will be interviewed to get to know in what circumstances they do their treatment. Items that are discussed are: - using rubber dam; - using magnification by means of loupes/microscope; - scheduled time for the treatment; - number of restorations after following the course. Initial data (gathered directly after treatment) will be evaluated looking at: - surface of preparation after IDS; - size of the prepared surface; - color. Follow up data will be evaluated looking at: - tooth extraction - fracture restoration - fracture tooth - secondairy caries - de-bonding - endodontic problems Outcome: Failures (fracture, de-bonding, secondairy cariës, endodontic problems) are the main outcome measurements. Description and estimation of the load and risk for the subjects: No extra intervention is performed. The dental practitioners will provide their data (i.e. impressions, occlusal light photo's) and these will be evaluated by the researchers. Follow up data will be gathered from X-rays already made for periodical oral examination (taking the caries risk into account). Summarizing, there is no extra load or risk for the patients. Studie design Prospective practice-based research, multicenter.

NCT ID: NCT05257213 Recruiting - Clinical trials for Intrauterine Adhesion

Heparin Solution Versus Anti-adhesion Barrier Gel for Intrauterine Adhesions Prevention After Operative Hysteroscopy

Start date: February 14, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of intrauterine application of heparin solution to the use of hyaluronic acid barrier gel for the prevention of intrauterine adhesion formation after operative hysteroscopy.

NCT ID: NCT05255081 Completed - Surgical Adhesions Clinical Trials

Evaluating Clinical Effects of a Spray-Type Bio-absorbable Adhesion Barrier System in Paediatric Patients

PEARL
Start date: March 1, 2022
Phase: N/A
Study type: Interventional

This is a prospective randomized single-blind study where a placebo group served the control, to confirm the efficacy and safety of AdSpray™ as an inhibitory effect of postoperative adhesion formation in paediatric patients who underwent laparotomy with stoma.

NCT ID: NCT05106400 Completed - Healthy Clinical Trials

Clinical Adhesion Study Between ZTlido 1.8% and Three Over-the-counter External Analgesic Lidocaine-containing Patches

Start date: July 1, 2021
Phase: Phase 1
Study type: Interventional

The study is designed to evaluate and compare the clinical adhesion performance of the ZTlido (Lidocaine Topical System) 1.8% of Scilex Pharmaceuticals Inc. (Reference) versus Salonpas (Lidocaine Patch 4%), Aspercreme (Lidocaine Patch 4%) and IcyHot (Lidocaine 4% + Menthol 1% Patch), on the Mid to upper back while being worn for 12 hours in healthy adult human subjects.