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Tinnitus clinical trials

View clinical trials related to Tinnitus.

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NCT ID: NCT00878696 Completed - Tinnitus Clinical Trials

Influence of Tonic and Burst Transcranial Magnetic Stimulation (TMS) Characteristics on Acute Inhibition of Subjective Tinnitus

Start date: January 2007
Phase: N/A
Study type: Observational

Transcranial magnetic stimulation (TMS) is already broadly used in different areas of neuroscience research. Last year, special attention was drawn to TMS in tinnitus. The aim of the researchers' study is to investigate the stimulation characteristics of TMS in tinnitus patients, in particularly the effect of tonic and burst stimulation of the superior temporal lobe.

NCT ID: NCT00876720 Completed - Tinnitus Clinical Trials

Effectiveness Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Chronic Tinnitus

Start date: April 2009
Phase: N/A
Study type: Interventional

Transcranial Magnetic Stimulation is used to modulate the auditory neural pathways caused by hearing loss and leading to the phantom auditory perception of sound in the absence of an external or internal acoustic stimulus.

NCT ID: NCT00860808 Completed - Tinnitus Clinical Trials

Efficacy of AM 101 in Patients With Acute Inner Ear Tinnitus

Start date: March 2009
Phase: Phase 2
Study type: Interventional

The purpose of the study is the evaluation of the therapeutic benefit of intratympanic AM 101 injections in comparison to placebo in the treatment of persistent acute inner ear tinnitus following acute sensorineural hearing loss.

NCT ID: NCT00841230 Completed - Tinnitus Clinical Trials

Deanxit and Rivotril in Tinnitus Patients

Start date: February 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate whether increased tinnitus reduction can be obtained with Deanxit in patients already receiving Rivotril.

NCT ID: NCT00833950 Completed - Tinnitus Clinical Trials

Phase Out in Tinnitus Patients

Start date: March 2008
Phase: Phase 4
Study type: Interventional

Phase shift treatment is a new tinnitus therapy that aims at sound cancelling via complete or partial residual inhibition. This technique is based on the theory by Choy advocating that the induction of a sound wave with a 180 degree phase shift compared to the sound experienced by the patient could result in sound cancelling, likely by negation of the cortical perception of tinnitus. The aim is to determine the efficacy of the Phase Out treatment in pure tone and narrow band noise tinnitus patients.

NCT ID: NCT00772980 Completed - Subjective Tinnitus Clinical Trials

Efficacy, Safety and Tolerability of Neramexane in Comparison to Placebo in Patients With Subjective Tinnitus

Start date: November 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of subjective tinnitus in comparison to placebo.

NCT ID: NCT00748475 Completed - Tinnitus Clinical Trials

Countering Stimulus-Induced Alpha-Desynchronization to Treat Tinnitus

Start date: September 2008
Phase: N/A
Study type: Interventional

The purpose of the study is to examine the effect of alpha-neurofeedback while subjects listen to a noise on tinnitus.

NCT ID: NCT00739635 Completed - Subjective Tinnitus Clinical Trials

Efficacy, Safety and Tolerability of Neramexane in Patients With Subjective Tinnitus

EASE
Start date: September 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of subjective tinnitus in comparison to placebo.

NCT ID: NCT00733044 Completed - Tinnitus Clinical Trials

Cost-effectiveness of Multidisciplinary Management of Tinnitus

Start date: September 2007
Phase: N/A
Study type: Interventional

Background: Tinnitus is a common chronic health condition that affects 10% to 20% of the general population. Among severe sufferers it causes disability in various areas. As a result of the tinnitus quality of life is often impaired. At present there is no cure or uniformly effective treatment, leading to fragmentized and costly tinnitus care. Evidence suggests an integral multidisciplinary approach in treating tinnitus is effective. The main objective of this study is to examine the effectiveness, costs, and cost-effectiveness of an integral treatment provided by a specialized tinnitus center versus usual care. This paper describes the study protocol. Methods/Design: In a randomized controlled clinical trial 198 tinnitus patients will be randomly assigned to a specialized tinnitus care group or a usual care group. Adult tinnitus sufferers referred to the audiological centre are eligible. Included patients will be followed for 12 months. Primary outcome measure is generic quality of life (measured with the Health Utilities Index Mark III). Secondary outcomes are severity of tinnitus, general distress, tinnitus cognitions, tinnitus specific fear, and costs. Based on health state utility outcome data the number of patients to include is 198. Economic evaluation will be from a societal perspective. Discussion/ Conclusion: This is, to our knowledge, the first randomized controlled trial that evaluates an integral treatment of tinnitus that includes a full economic evaluation from a societal perspective. If this intervention proves to be effective and cost-effective, implementation of this intervention is considered and anticipated.

NCT ID: NCT00724152 Completed - Tinnitus Clinical Trials

Cognitive Behavioral Therapy (CBT) for Tinnitus

Start date: February 2009
Phase: Phase 1/Phase 2
Study type: Interventional

This study examined how useful it is to teach veterans coping skills for dealing with tinnitus, also called ringing in the ears. A psychological intervention, cognitive-behavioral therapy, was used to teach coping skills even though tinnitus is not a psychological disorder. Participants in Period 1 of the study were assigned to one of two groups for the duration of the study and were blinded to their group assignment until the end of the study. One group received education about tinnitus. The other group received education about tinnitus plus additional ways to cope with problems associated with tinnitus such as sleep disturbance and frustration. Participants were selected to participate if their tinnitus was severe and they had been exposed to loud sound. Participants attended up to six weekly group meetings. It was predicted that participants who were randomly assigned to the cognitive behavioral therapy group would report a greater reduction in tinnitus severity than education controls. During Period 2 of the study, a third "standard care" arm was added. Baseline and outcome data of the 4 participants who completed the study after this third arm was added to the study design are not reported.