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Tinnitus, Subjective clinical trials

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NCT ID: NCT05343026 Not yet recruiting - Clinical trials for Tinnitus, Subjective

Efficacy of Hearing-aid Treatment for Patients With Tinnitus and Co-existing Hearing Loss

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Considering the extent to which HAs play a role in sound perception and residual hearing preservation among patients with tinnitus and co-existing HL remains a lack of compelling extensive evidence, investigators designed this single-blind, 6-months randomized, controlled trial with two parallel groups. One is the HA treatment group, and the other is the waiting list control (WLC) group which receives no interventions during this period.

NCT ID: NCT05271825 Completed - Clinical trials for Tinnitus, Subjective

Broadband Amplification as Tinnitus Treatment

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

- The effect of broadband amplification was tested in a double-blinded crossover study - Its effect was compared to an active placebo treatment - An improvement in tinnitus distress was found after use of broadband amplification - No effect was found on the tinnitus loudness

NCT ID: NCT05268770 Not yet recruiting - Inflammation Clinical Trials

Inflammation in Tinnitus

INFLATIN
Start date: March 2022
Phase:
Study type: Observational [Patient Registry]

Rationale: Tinnitus is the perception of sound without an external source. In the past decade, inflammation has been implicated in the pathophysiology of tinnitus. In animal models of tinnitus, the expression of proinflammatory cytokines Tumor Necrosis Factor-α (TNF-α) and interleukine-1β (IL-1β) was increased throughout the whole auditory tract. Only two studies evaluated cytokine concentrations in tinnitus patients. In these studies an increase of IL-6 and decrease of IL-10 have been objectified. However, studies did not include tinnitus patients based on the degree of hearing loss, despite that inflammation has also been implicated in hearing loss. On the other hand, studies about inflammation in hearing loss did not (always) exclude tinnitus. Thus, it remains unclear whether the upregulated cytokine concentrations the studies are specific for tinnitus, and whether potential effects remained unsignificant because the presence of hearing loss is a confounder. Therefore, the aim of this study is to evaluate the presence of inflammation in tinnitus patients with normal hearing. Objective: The main objective is to evaluate the presence of inflammation in blood samples of human subjects with tinnitus and normal hearing, compared to healthy controls. The secondary objective is to evaluate the relation between tinnitus severity and inflammatory marker concentrations. Study design: This is a cross-sectional study. Study population: Patients who have been referred to the tinnitus consultation at the outpatient clinic will be asked to participate in this study. For the control group, healthy volunteers will be recruited. Main study parameters/endpoints: The main study parameter is the disparity in blood cytokine levels between participants with and without tinnitus. Secondary study parameters are the relation between tinnitus severity and blood cytokine concentration, and the difference in complete blood count measures in participants with and without tinnitus.

NCT ID: NCT05198973 Recruiting - Clinical trials for Tinnitus, Subjective

Bumblebee Breath Effect on Tinnitus in Older Patients

Start date: November 8, 2021
Phase: N/A
Study type: Interventional

Tinnitus is a condition in which the person hears sound, which isn't coming from the external environment, often, described as ringing in the ears. Patients describe the condition as an annoyance and disturbance and in turn this correlates with increased levels of anxiety and depression. Currently, there is no single effective treatment for tinnitus so research continues to look for new ways to treat and manage the condition. Bumblebee Breath starts by finding a relaxed, supported posture, either laying supine or in seated and then bringing the minds attention to the space between the eyebrows (or third eye in yoga terms). With the eyes close the thumbs are placed over the tragus of the ears, the first finger gently rests on eye lids, middle finger touches the sides of the nose and then the index and pinkie rest just above and below the closed lips. Next, a sound is created by inhaling deeply through the nose and exhaling with a low-pitched humming sound. The result sounds very much like a bee buzzing to the person performing the breath and a sensation of vibration is experienced inside the head and over the face. this study is designed to assess Bumblebee Breath on tinnitus.

NCT ID: NCT05188365 Recruiting - Obesity Clinical Trials

Acupuncture Efficacy on Lipids in Tinnitus Patients With Obesity

Start date: December 6, 2021
Phase: N/A
Study type: Interventional

nowadays, published literature affirms strong relation between tinnitus, obesity, and high lipids of blood.

NCT ID: NCT05120037 Completed - Clinical trials for Tinnitus, Subjective

MRI Study of High Definition Transcranial Electrical Stimulation in Chronic Tinnitus (MRI HDtES-T)

MRI HDtES-T
Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this research is to understand how a neurostimulation technique, transcranial electrical stimulation (tES), affects brain function in adults with chronic subjective tinnitus measured with functional magnetic resonance imaging (fMRI). This study targets a specific kind of tES called transcranial direct current stimulation (tDCS), where a mild, constant current is passed between electrodes placed on the scalp.

NCT ID: NCT04987502 Recruiting - Tinnitus Clinical Trials

Virtual Reality and Subjective Tinnitus

ReVA2
Start date: September 7, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to test if virtual reality immersion has the potential to significantly decrease subjective tinnitus intrusiveness when compared to standard care.

NCT ID: NCT04934371 Not yet recruiting - Clinical trials for Tinnitus, Subjective

Treatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy

TDCS
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to use non-invasive transcranial direct current stimulation (tDCS) combined with active listening therapy to treat tinnitus and hyperacusis and related conditions.

NCT ID: NCT04800107 Active, not recruiting - Clinical trials for Tinnitus, Subjective

Effect of Highly Bioavailable Curcumin on Subjective Tinnitus

Start date: January 6, 2021
Phase: N/A
Study type: Interventional

This study will assess the effectiveness of highly bioavailable curcumin in suppressing subjective tinnitus based on pre- and post-treatment evaluations using the validated Tinnitus Functional Index (TFI) and Tinnitus Handicap Inventory (THI) surveys.

NCT ID: NCT04641156 Completed - Clinical trials for Tinnitus, Subjective

Effect of Physical Therapy Exercise Program and Low-Level Laser Therapy on the Treatment of Cervicogenic Somatosensory Tinnitus

Start date: December 10, 2018
Phase: N/A
Study type: Interventional

To determine the effectiveness of adding a physical therapy exercise program to low-level laser therapy on the treatment of chronic tinnitus treatment