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Tinnitus, Subjective clinical trials

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NCT ID: NCT06433895 Not yet recruiting - Clinical trials for Tinnitus, Subjective

Efficacy of Manual Therapy in the Treatment of Somatic Tinnitus

Start date: May 25, 2024
Phase: N/A
Study type: Interventional

Somatic tinnitus is an unpleasant perception of sound that occurs in the absence of any external acoustic stimulus. Despite the correct diagnosis of somatic tinnitus, there is currently no specific treatment. The hypothesis of this study is that the application of manual therapy to the cervical region will help to treat tinnitus in patients. This study aims to investigate the effectiveness of manual therapy in the treatment of somatic tinnitus of cervicogenic origin.

NCT ID: NCT06423742 Completed - Clinical trials for Tinnitus, Subjective

Consecutive Dual-Session tDCS in Chronic Subjective Severe to Catastrophic Tinnitus With Normal Hearing

Start date: December 15, 2021
Phase: N/A
Study type: Interventional

We aimed to analyze the effect of continuous dual session tDCS in patients with severe chronic subjective tinnitus without any evidence of hearing loss in terms of relief of tinnitus perception, distress, and loudness. Also, we investigated the difference in the maintenance duration of the tinnitus suppression effect of consecutive dual session tDCS compared to other groups followed up for 2 months.

NCT ID: NCT06360731 Active, not recruiting - Clinical trials for Tinnitus, Subjective

The Effect of 4-7-8 Breathing Exercise Technique on Tinnitus

Start date: March 18, 2024
Phase: N/A
Study type: Interventional

The goal of this study is to evaluate the effect of 4-7-8 breathing exercise on tinnitus handicap, psychological factors and sleep quality. There will be a parallel-group randomized controlled trial study and consists of two groups. Both groups will receive 1 hour of informative session on tinnitus and the experimental group will also perform 4-7-8 breathing exercises for 6 weeks. Visual analog scale, tinnitus handicap inventory, insomnia severity index, trait anxiety inventory, and perceived stress scale will be applied before and after the application.

NCT ID: NCT05964725 Recruiting - Clinical trials for Transcranial Direct Current Stimulation

The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus

Start date: November 23, 2023
Phase: N/A
Study type: Interventional

This clinical study is prospective, single-center, randomized, controlled, double-blind clinical trail, which entitled transcranial electrical stimulation for the treatment of acute tinnitus approved by Sun Yat-sen University, and intends to recruit 86 patients with sudden deafness and tinnitus. For acute subjective tinnitus, a common otological disease, the study gave the experimental group patients received tDCS with electrodes positioned over the left temporal cortex for 5 days. To assess the efficacy of conventional medical therapy and tDCS by comparing changes in anterior and posterior tinnitus-related subjective scale scores, such as THI, VAS, BAI, BDI, PSQI, and hearing recovery, in patients who received tDCS, to determine whether tDCS is effective in improving acute tinnitus, and whether it is superior to conventional tinnitus treatment. In addition, the study will continue to follow patients for 1 month,3 months, and 6 months after the end of treatment to observe the long-term sustained efficacy of tDCS. This clinical trail will also evaluate tDCS from the perspective of compliance and safety, and explore the factors affecting the efficacy of this therapy.

NCT ID: NCT05871294 Recruiting - Clinical trials for Tinnitus, Subjective

Cohort Study on Biomarkers and Clinical Treatment of Tinnitus

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to search for biomarkers in tinnitus patients in tinnitus patients and changes in biomarkers before and after treatment. The main questions it aims to answer are: - What are the biomarkers of tinnitus patients? - How do these biomarkers change during treatment and is there a good correlation with behavioral outcomes? Participants will be asked to complete audiological examination, tinnitus assessment, and magnetoencephalography examination, and they will receive sound therapy or repetitive transcranial magnetic stimulation therapy.

NCT ID: NCT05830604 Completed - Clinical trials for Temporomandibular Disorder

Evaluation of the Effect of Muscle Activity on Subjective Tinnitus in Temporomandibular Disorders

Start date: December 21, 2021
Phase: N/A
Study type: Interventional

Treatment of Temporomandibular Joint Disorder can help reduce subjective tinnitus levels. This treatment changes the electrical activity of the patient's chewing muscles. For this reason, the relationship between muscular change and tinnitus levels can be evaluated.

NCT ID: NCT05711641 Completed - Clinical trials for Tinnitus, Subjective

Action of Intra-auricular Topical Lidocaine on Tinnitus

Start date: September 2, 2022
Phase: N/A
Study type: Interventional

The main objective of this clinical trial placebo controled is to evaluate the action of intraauricular topical lidocaine on tinnitus. The question to be answered is whether lidocaine is superior to placebo (distilled water) in reducing tinnitus intensity when applied topically within the external auditory canal. Tinnitus intensity will be measured using the visual analog scale and acuphenometry before and after lidocaine or placebo application.

NCT ID: NCT05646693 Recruiting - Oxidative Stress Clinical Trials

Effect of Combined Antioxidant Therapy on Oxidative Stress Markers and Inflammatory Cytokines in Patients With Tinnitus

Start date: December 1, 2022
Phase: Phase 2
Study type: Interventional

The main objective of our study is to evaluate the effect of combinated antioxidants therapy with Adepsique® (amitriptyline, perphenazine, and diazepam) on patients with tinnitus chronic symptoms, evaluating the levels of inflammatory cytokines and oxidative stress in blood. The researchers intend to include 58 patients, divided into two intervention groups, who will be randomly assigned a pill with antioxidants or placebo, and the patient must eat one pill per day for 3 months. In the study, the clinical characteristics of tinnitus, inflammatory cytokines and oxidative stress markers will be evaluated, before, during and after the intervention with antioxidant therapy. Subsequently, the clinical and sample results will be evaluated to compare the effects between them.

NCT ID: NCT05591144 Completed - Clinical trials for Tinnitus, Subjective

Short-term Oral Prednisone for Acute Subjective Tinnitus

STOP-FAST
Start date: October 30, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate the efficacy of oral steroids in the acute tinnitus population. Participants will receive appropriate dosages of short-term prednisone and/or oral Ginkgo Biloba tablets.

NCT ID: NCT05557357 Recruiting - Tinnitus Clinical Trials

Electroacupuncture With or Without Combined Warm Needling for Tinnitus

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

This randomized controlled trial aims to evaluate the efficacy and safety of either electroacupuncture alone or combined with warm needling in reducing tinnitus loudness and improving the impairment caused by tinnitus in Hong Kong.