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NCT01103557 Clinical Trial

Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma

Thyroid Neoplasm Clinical Trial

Official title:
The Effectiveness of Prophylactic Selective Lateral Neck Dissection in Papillary Thyroid Carcinoma Patients With Central Neck Metastasis

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01103557
Other study ID # PTC_CND_LND
Secondary ID
Status Completed
Phase N/A
First received April 12, 2010
Last updated April 13, 2010

Study information
Verified date January 2010
Source Pusan National University Hospital
Contact n/a
Is FDA regulated No
Health authority Korea: Institutional Review Board
Study type Interventional

Clinical Trial Summary

The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by performing prophylactic selective lateral neck dissection (SND).

Description:

The lymphatic drainage pattern of the thyroid is uniform and consistent, and therefore, metastatic patterns are relatively predictable. Initial nodal metastasis in PTC usually occurs in the paratracheal and pretracheal nodes in level VI of the central compartment of the ipsilateral neck and spreads to the lateral cervical lymph nodes. Macroscopic skip metastases to the lateral compartment of the neck in the absence of central disease are uncommon.

Recruitment information / eligibility
Status Completed
Enrollment 62
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 20 Years to 76 Years
Eligibility Inclusion Criteria:

- Papillary thyroid carcinoma with central neck metastasis

- No evidence of lateral neck metastasis as determined by high-resolution neck ultrasonography and computed tomography

Exclusion Criteria:

- History of previous thyroid operation

- Isthmic thyroid lesion

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Intervention

Procedure:
• prophylactic selective lateral neck dissection
Level II, III, IV lymph node dissection

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Pusan National University Hospital
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