Thumb Osteoarthritis Clinical Trial
Official title:
The Role of the Proprioceptive Training in Functional Recovery of Patient With Thumb Base Osteoarthritis. A Multicenter Experimental Study
NCT number | NCT04892589 |
Other study ID # | 2021 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | May 30, 2021 |
Est. completion date | February 2022 |
Diseases that have implications for the thumb impact its function, and consequently, people occupational performance. Carpometacarpal joint (CMC) thumb degeneration translates into osteoarthritis (OA). Joint congruence, ligament integrity and compression of the joint surfaces caused by muscle contraction have historically been considered the three basic pillars for carpus stability. In recent years, a new factor has been proposed to explain carpal stabilization mechanisms: proprioception. The dorsal ligament complex is the structure with the highest concentration of mechanoreceptors, especially Ruffini's corpuscles. This study aims to detect the effect of proprioceptive training on the functional recovery of people with CMC osteoarthritis in conservative treatments.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | February 2022 |
Est. primary completion date | December 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 90 Years |
Eligibility | Inclusion Criteria: - Diagnosis of grade I, II or III thumb CMC joint OA in their dominant hand according to the Eaton Classification Stage - Pain rating of 4/10 on the Visual Analogue Scale (VAS) during activities of daily living (ADLs) at the time of the therapy initial evaluation. - The ability to read and understand the patient information sheets and exercises. - A minimum thumb abduction capacity of 40º. Exclusion Criteria: - Previous hand and wrist surgeries, neurological disorders, diagnosis of OA that includes the wrist, rheumatoid arthritis, or any implication of an osteomyoarticular nature in the hand and / or wrist other than the CMC OA. - Had received specific treatment for hand or thumb pain in the same limb in the last 6 months including an intra-articular joint injection to wrist, fingers, or thumb. |
Country | Name | City | State |
---|---|---|---|
Argentina | Clínica Universitaria Reina Fabiola | Córdoba | |
Spain | Centro TECAN Clinica de la Mano | Málaga |
Lead Sponsor | Collaborator |
---|---|
Clinica Universitaria Reina Fabiola, Universidad Catolica de Cordoba |
Argentina, Spain,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Visual Analogue Scale (VAS) | Visual Analogue Scale has been shown to be a reliable and valid instrument for pain assessment which is used frequently for clinical and research purposes. It consists of a 10-cm line anchored at each end. The left-hand anchor reads 'no pain' score 0 and the right-hand anchor reads 'worst possible pain' score 10; the patients marked a line to represent their pain level. | Change from baseline pain at 4 weeks. | |
Primary | Visual Analogue Scale (VAS) | Visual Analogue Scale has been shown to be a reliable and valid instrument for pain assessment which is used frequently for clinical and research purposes. It consists of a 10-cm line anchored at each end. The left-hand anchor reads 'no pain' score 0 and the right-hand anchor reads 'worst possible pain' score 10; the patients marked a line to represent their pain level. | Change from 4 weeks pain at 12 weeks. | |
Primary | Australian Canadian Osteoarthritis Hand Index version (AUSCAN) | To assess the affection of the hands in rheumatic diseases, with good discriminatory capacity The functional capacity assessment subscale will be used, which provides specific data on the subject's ability to open / close water taps; turn the door handles / knobs; buttoning up; fastening / unbuttoning jewelry; open a new bottle; load a full pot; peel fruits and vegetables; lift large and heavy objects; wring out wet clothes / sponges or rags. This functional subscale evaluates from 9 to 45, with 9 being "no difficulty" and 45 "extreme difficulty" | Change from baseline hand function at 4 weeks. | |
Primary | Australian Canadian Osteoarthritis Hand Index version (AUSCAN) | To assess the affection of the hands in rheumatic diseases, with good discriminatory capacity The functional capacity assessment subscale will be used, which provides specific data on the subject's ability to open / close water taps; turn the door handles / knobs; buttoning up; fastening / unbuttoning jewelry; open a new bottle; load a full pot; peel fruits and vegetables; lift large and heavy objects; wring out wet clothes / sponges or rags. This functional subscale evaluates from 9 to 45, with 9 being "no difficulty" and 45 "extreme difficulty" | Change from 4 weeks hand function at 12 weeks. | |
Secondary | Joint position Sense (JPS) | Proprioception using active joint position sense (JPS) has been utilized in studies to establish a correlation between therapy intervention and proprioception. The target position of 30 degree CMC abduction will be selected. Joint angle will be measured using a standard clear plastic goniometer. | baseline-4 and 12 weeks | |
Secondary | Canadian Occupational Performance Measure | Patient's occupational performance will be measured with the Canadian Occupational Performance Measure (COPM).
The COPM enables subjects to identify goals for hand therapy and engage in a subject-specific therapeutic process. It has been established that the COPM has good convergent validity and responsiveness for evaluating the relationship between patient self-perception and satisfaction for patients with CMC thumb OA . |
baseline-4 and 12 weeks | |
Secondary | Force Sense | Patient's sensation force will be measured with the Force Sense. | baseline-4 and 12 weeks |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04913935 -
Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA
|
||
Terminated |
NCT04613154 -
Magnesium as an Adjunct for Pain Treatment After Surgery for Thumb Base Arthrosis
|
N/A | |
Not yet recruiting |
NCT06401317 -
Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)
|
N/A | |
Completed |
NCT05772715 -
The THumb Osteoarthritis Exercise TriAl
|
N/A | |
Not yet recruiting |
NCT05095415 -
Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting
|
N/A | |
Active, not recruiting |
NCT03611023 -
Study of the Touch® Trapezo-metacarpal Prosthesis
|
||
Completed |
NCT03858946 -
Ligament Reconstruction Weilby vs Simple Trapeziectomy
|
N/A | |
Recruiting |
NCT05626192 -
Anatomical Evaluation of the APL Tendons in Thumb CMC Joint and Osteoarthritis
|
||
Recruiting |
NCT04210687 -
Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis
|
N/A | |
Recruiting |
NCT04826380 -
Thumb Basal Joint (CMC I) Arthritis - Preoperative Anxiety/Depression, Outcome Instruments, Carpal Cinematics and Cost-utility
|
N/A | |
Completed |
NCT04738201 -
Proprioceptive Thumb Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
|
N/A | |
Recruiting |
NCT04625244 -
Can Video Assisted Therapy Replace In-Person Occupational Therapy After Hand Surgery: A Noninferiority Study
|
N/A | |
Recruiting |
NCT01679717 -
Postoperative Therapy After Interposition Arthroplasty in CMC1
|
N/A | |
Active, not recruiting |
NCT05315297 -
Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis
|
N/A | |
Not yet recruiting |
NCT05896410 -
3D-Printed Hand Orthosis Versus Thermoplastic Orthosis
|
N/A | |
Not yet recruiting |
NCT04588961 -
Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis
|
N/A | |
Recruiting |
NCT05992883 -
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
|
Phase 3 | |
Completed |
NCT02958137 -
Arthroscopic Resection Arthroplasty of Carpometacarpal and/or Pantrapezial Osteoarthritis
|
N/A | |
Recruiting |
NCT05127005 -
Efficacy of Trapeziectomy Versus Sham Surgery in the Treatment of Osteoarthritis at the Base of the Thumb
|
N/A | |
Completed |
NCT04669704 -
Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers.
|
N/A |