Clinical Trials Logo
  1. Home
  2. Thumb Osteoarthritis
  3. NCT04613154

Magnesium as an Adjunct for Pain Treatment After Surgery for Thumb Base Arthrosis

Thumb Osteoarthritis Clinical Trial

Official title:
Magnesium as an Adjunct for Pain Treatment After Surgery for Thumb Base Arthrosis, a Randomised Controlled Study

Clinical Trial Summary

A randomised controlled trial of addition to the standard pain treatment of 1000 mg oral magnesium citrate or placebo for 7 Days during surgery for thumb base arthrosis. Intraoperative nociception will be measured with the NoL-index with a PM-200 machine.

Clinical Trial Description

Our hypothesis is that an addition of oral 1000 mg magnesium citrate daily for 7 Days starting at the day of the surgery will decrease the postoperative pain and improve the recovery after surgery. It will be given as an supplement to the regular pain treatment with acetaminophen and oxycodone that are used in our hospital and compared to a placebo. The choice of treatment will be blinded for the patient, the care providers and for the research team doing the evaluation. The pain level will be collected Before surgery, postoperatively and at 14 Days after surgery and by a self reporting form during the first 7 Days. The patients will also report their recovery with a modified QoR-15 form. QoR-15 is validated in a Swedish version. Magnesium is shown to reduce postoperative pain in some studies that used iv magnesium sulphate. For long lasting pain conditions oral magnesium is shown to improve the patients well being and decrease their pain in some conditions. Magnesium acts as a mild antagonist at the NMDA-receptor. Thus low levels of magnesium is thought to increase the risk of long lasting postoperative pain. Therefore there are reason to expect a higher dose of magnesium supplement decreases the long lasting post operative pain. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04613154
Study type Interventional
Source Region Örebro County
Contact
Status Terminated
Phase N/A
Start date September 24, 2020
Completion date October 10, 2023
View Details
See also
  Status Clinical Trial Phase
Completed NCT04913935 - Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA
Completed NCT05772715 - The THumb Osteoarthritis Exercise TriAl N/A
Not yet recruiting NCT05095415 - Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting N/A
Active, not recruiting NCT03611023 - Study of the Touch® Trapezo-metacarpal Prosthesis
Completed NCT03858946 - Ligament Reconstruction Weilby vs Simple Trapeziectomy N/A
Recruiting NCT05626192 - Anatomical Evaluation of the APL Tendons in Thumb CMC Joint and Osteoarthritis
Recruiting NCT04892589 - The Role of the Proprioceptive Training in Functional Recovery of Patient With Thumb Base Osteoarthritis
Recruiting NCT04210687 - Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis N/A
Recruiting NCT04826380 - Thumb Basal Joint (CMC I) Arthritis - Preoperative Anxiety/Depression, Outcome Instruments, Carpal Cinematics and Cost-utility N/A
Completed NCT04738201 - Proprioceptive Thumb Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis N/A
Recruiting NCT04625244 - Can Video Assisted Therapy Replace In-Person Occupational Therapy After Hand Surgery: A Noninferiority Study N/A
Recruiting NCT01679717 - Postoperative Therapy After Interposition Arthroplasty in CMC1 N/A
Recruiting NCT05315297 - Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis N/A
Not yet recruiting NCT05896410 - 3D-Printed Hand Orthosis Versus Thermoplastic Orthosis N/A
Not yet recruiting NCT04588961 - Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis N/A
Recruiting NCT05992883 - NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis Phase 3
Completed NCT02958137 - Arthroscopic Resection Arthroplasty of Carpometacarpal and/or Pantrapezial Osteoarthritis N/A
Recruiting NCT05127005 - Efficacy of Trapeziectomy Versus Sham Surgery in the Treatment of Osteoarthritis at the Base of the Thumb N/A
Completed NCT04669704 - Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers. N/A
Recruiting NCT04455763 - Autologous Stromal Vascular Fraction in the Treatment of Thumb Basal Joint Osteoarthritis N/A