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NCT03017118 Clinical Trial

Turmeric for Patients With Basal Joint Arthritis

Thumb Osteoarthritis Clinical Trial

Official title:
A Randomized Controlled Trial Using Turmeric for Patients With Basal Joint Arthritis

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03017118
Other study ID # 2016P001402
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date August 9, 2017
Est. completion date December 2024

Study information
Verified date June 2023
Source Massachusetts General Hospital
Contact Neal Chen, M.D.
Phone 617-726-4700
Email nchen1@mgh.harvard.edu
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.

Recruitment information / eligibility
Status Recruiting
Enrollment 20
Est. completion date December 2024
Est. primary completion date December 2024
Accepts healthy volunteers No
Gender All
Age group 40 Years and older
Eligibility Inclusion Criteria: - 40 years of age or older - English fluency and literacy - Seeking care for basal joint pain - Tender over basal joint - Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction) - Radiographic evidence of Eaton stage 1 and 2 only Exclusion Criteria: - Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment - Inability or unwillingness to participate in a trial study - Rheumatoid Arthritis or other inflammatory disorder diagnoses - Post-traumatic osteoarthritis - Patients on Coumadin/Steroids/NSAIDs/Tylenol - Diabetes Mellitus - Pregnant or lactating women - Basal joint arthritis of Eaton stage 3 - Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)

Study Design

Related Conditions & MeSH terms

Intervention

Dietary Supplement:
• Turmeric
Subjects will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.
Other:
• Placebo
Subjects in the control group will receive a placebo 3 times per day for 6 weeks.

Locations
Country Name City State
United States Massachusetts General Hospital Boston Massachusetts

Sponsors (1)
Lead Sponsor Collaborator
Massachusetts General Hospital

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in baseline pain intensity 0-10 ordinal rating of pain intensity Enrollment, 6 weeks, and 3 months
Primary Change in baseline disability Disability measured by the QuickDASH Enrollment, 6 weeks, and 3 months
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