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Thrombosis clinical trials

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NCT ID: NCT02205827 Completed - Healthy Clinical Trials

A Study to Determine the Inter/Intra Observer and Intra-subject Variability of Whole Blood Clotting Time Measurements

Start date: April 2014
Phase: N/A
Study type: Interventional

The purpose of the study is to characterize the distribution and sources of variability in whole blood clotting time (WBCT) measurements in human blood collected from healthy volunteers by 5 different technicians.

NCT ID: NCT02205294 Completed - Clinical trials for Deep Vein Thrombosis (DVT)

Osteopathic Treatment and Deep Vein Thrombosis (DVT)

Start date: November 6, 2014
Phase: N/A
Study type: Interventional

Osteopathic treatment will provide: 1. A significant reduction of pain and swelling of the affected DVT leg 2. An increase in the quality of life (QOL) for individuals with DVT of the leg 3. Improved signs and symptoms of the post thrombotic syndrome of the affected DVT leg

NCT ID: NCT02186223 Completed - Pulmonary Embolism Clinical Trials

The Angel® Catheter Clinical Trial

Start date: January 2015
Phase: N/A
Study type: Interventional

The primary objective of this multicenter, prospective, single arm clinical trial is to evaluate the safety and effectiveness of the Angel® Catheter in subjects at high risk of PE, and with recognized contraindications to standard pharmacological therapy (anticoagulation).

NCT ID: NCT02161965 Completed - Pulmonary Embolism Clinical Trials

Vascular CalcIfiCation and sTiffness Induced by ORal antIcoAgulation

VICTORIA
Start date: May 21, 2013
Phase: Phase 4
Study type: Interventional

The VICTORIA Study (Vascular CalcIfiCation and sTiffness induced by ORal antIcoAgulation) is a comparative, parallel, prospective, controlled and randomized study of the structural and functional impact of rivaroxaban versus anti-vitamin K drugs on the arterial vasculature.

NCT ID: NCT02159521 Completed - Clinical trials for Deep Vein Thrombosis

Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System

ACCESS PTS
Start date: July 10, 2014
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy of ultrasound accelerated thrombolysis using the EkoSonic® Endovascular System with standard infusion of thrombolytic drug for post-thrombotic syndrome from chronic venous occlusion.

NCT ID: NCT02158403 Completed - Clinical trials for HeartMate II Pump Thrombosis

PREVENtion of HeartMate II Pump Thrombosis

PREVENT
Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to assess how often blood clots form in the FDA-approved HeartMate® II (HM II) Left Ventricular Assist Device (LVAD) and to identify risks related to clotting within the pump.

NCT ID: NCT02155491 Completed - Pulmonary Embolism Clinical Trials

Global Anticoagulant Registry in the FIELD- Venous Thromboembolic Events

GARFIELD-VTE
Start date: July 7, 2014
Phase:
Study type: Observational [Patient Registry]

The protocol is a large registry to describe acute, sub-acute and extended duration of anticoagulation management, clinical and economic duration of anticoagulation management, clinical and economic outcomes in patients with treated acute VTE (DVT and PE) in the real-world setting. Main objectives are to clarify the: - treatment related details for acute VTE (either conventional anticoagulation therapy, treatment with a direct oral anti-coagulant or other modalities of treatment) - Rate of early and late symptomatic VTE recurrence - Rate and nature of complications of VTE including post thrombotic syndrome and chronic thromboembolic pulmonary hypertension - Rate of bleeding complications - Rate of all-cause mortality at six months

NCT ID: NCT02148757 Completed - Clinical trials for Number of Deep Venous Thrombosis (DVT)

Doppler Ultrasound Following Unicondylar Knee Replacement to Determine the Incidence of Postoperative DVT

Start date: June 2011
Phase: N/A
Study type: Interventional

Purpose of this study is to determine the incidence of deep venous thrombosis after partial knee replacement.

NCT ID: NCT02148029 Completed - Clinical trials for Acute Deep Vein Thrombosis

Role of a Novel Exercise Program to Prevent Post-thrombotic Syndrome

EFFORT2
Start date: July 1, 2014
Phase: N/A
Study type: Interventional

Despite standard care, 25%-50% of patients with clots in the deep veins of the arms and legs progress to chronic post-clot problems resulting in significant disability, loss of productivity, and healthcare costs. Reverse flow in the veins from an organizing clot is the primary cause of post-clot problems. Veins with early clot breakdown have a lower incidence of reverse flow. The investigators have observed that clot breakdown is enhanced by increased blood flow and that moderate arm and leg exercise result in increased venous blood flow. Hence, the investigators predict that a supervised exercise program in patients with deep vein clots could increase leg vein blood flow, accelerate clot breakdown, and decrease the risk of post clot problems. The primary hypothesis is that increased blood flow across the clot (induced by supervised exercise) will increase clot breakdown and decrease severity of post clot problems. The investigators are conducting a randomized clinical trial of standard therapy compared to progressive exercise training in patients with leg deep vein clots.

NCT ID: NCT02140801 Completed - Thrombosis Clinical Trials

Optical Coherence Tomography to Evaluate Ticagrelor and Clopidogrel

Start date: May 1, 2014
Phase: Phase 4
Study type: Interventional

A number of 352 patients scheduled for elective percutaneous coronary intervention (PCI) with a native coronary stenosis suitable for DES implantation and OCT imaging are openly randomized 1:1 to either BRILINTAâ„¢ (ticagrelor) or Plavix® (clopidogrel bisulfate).