Thromboembolism Clinical Trial
Official title:
Assessment of Subclinical Atherosclerosis Using Dual-source Computed Tomography Coronary Angiography in Chinese Adults With Different Glycaemic Status
Part I: Survey of Coronary Artery Calcification and Stenosis in Participants with Different
Glycaemic Status
Aims:
To evaluate coronary artery calcification and stenosis in community-dwelling adults with
different glycaemic status, using dual-source CT angiography (CTA)
Study Subjects and Methods:
200 adults with normal glucose regulation (NGR), 200 with impaired glucose regulation (IGR)
and 200 with type 2 diabetes were recruited from an urban community of Shanghai, who then
underwent a comprehensive examination including questionnaire, anthropometric measurements,
biochemical analysis and CTA.
Part II: Follow-up of Cardiovascular Events and Re-evaluation of Coronary Artery
Calcification and Stenosis
Aims and Methods:
To investigate the development of cardiovascular diseases in subjects recruited in part I
and re-evaluate coronary artery calcification and stenosis using CTA after 3-year follow-up
To identify the predictive value of coronary artery calcification and stenosis with future
risks of cardiovascular diseases and the possible development of coronary artery disorders
among participants with different glycaemic status
n/a
Observational Model: Cohort, Time Perspective: Prospective
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