Direct Mechanical Thrombectomy Versus Bridging Therapy

Status Completed

Clinical Trial Summary

Clinical Trial Description

This study compares the efficacy and safety of direct mechanical thrombectomy versus bridging therapy in patients with anterior circulation large vessel occlusion in a cohort of patients treated at the stroke unit of a single centre at Alexandria University in Egypt. In the first arm, 17 patients were recruited and underwent direct mechanical thrombectomy without receiving recombinant tissue plasminogen activator. In the bridging therapy arm, 34 patients received first tissue plasminogen activator then underwent direct mechanical thrombectomy. The efficacy was evaluated by the NIHSS improvement 24 hours following stroke onset and the modified Rankin scale 3 months following stroke. Safety was assessed by the procedural complications rate especially the hemorhagic transformation. ;

Study Design

Related Conditions & MeSH terms

Atherosclerosis
Ischemic Stroke
Large-Artery Atherosclerosis (Embolus/Thrombosis)
Thrombectomy
Thrombosis

Clinical Trial Details

NCT number	NCT05155540
Study type	Interventional
Source	Alexandria University
Contact
Status	Completed
Phase	Phase 4
Start date	July 1, 2019
Completion date	September 1, 2020

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