Evaluation of the Alveolar Recruitment Obtained During Non-invasive Ventilation After Cardiac Surgery

Thoracic Surgery Clinical Trial

— ARCTICS  

Official title:

Evaluation of the Alveolar Recruitment Obtained During Non-invasive Ventilation After Cardiac Surgery

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02804997
• Other study ID #: PI2014_843_0020
• Status: Terminated
• Start date: May 13, 2015
• Est. completion date: January 27, 2017

Study information

• Verified date: September 2018
• Source: Centre Hospitalier Universitaire, Amiens
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The great majority of cardiac surgery patients develop a degree of post-operatory respiratory failure. This is due to several factors. The predominant element in the onset of this respiratory impairment is the constitution of foci of pulmonary atelectasis, caused by peroperative hypoventilation (in the presence or absence of ECC). The incidence has been evaluated at between 54% and 92%, depending on the study. The use of NIV (non-invasive ventilation) might (through the application of continuous positive expiratory pressure) help to counter the development of these atelectasic foci.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 17
• Est. completion date: January 27, 2017
• Est. primary completion date: January 27, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age =18

• in the post-operative phase after elective cardiac surgery for aortic or mitral valve replacement, coronary revascularization or mixed surgery, hypoxemia or hypercapnia, with an indication for NIV,

• hemodynamic stability

• prior consent

• spontaneous ventilation

• social security coverage.

Exclusion Criteria:

• Under-18 patients

• complex cardiac surgery

• pregnancy

• pre-existing chronic obstructive respiratory disease (COPD > stage II)

• legal guardianship

• incarceration

Related Conditions & MeSH terms

• Thoracic Surgery

Locations

Country	Name	City	State
France	CHU Amiens	Amiens

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire, Amiens

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Quantitative evaluation by thoracic CT scan	Quantitative evaluation performed by thoracic CT scan of alveolar recruitment induced by NIV after cardiac surgery	3 hours