Clinical Trials Logo

Thoracic Surgery clinical trials

View clinical trials related to Thoracic Surgery.

Filter by:

NCT ID: NCT03277391 Recruiting - Thoracic Surgery Clinical Trials

Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic Surgery

Serrathos
Start date: April 14, 2017
Phase: N/A
Study type: Interventional

The objective of the study is to compare the efficacy of the Serratus Anterior Plane block (SPB) realised in its deep plane, with a multi-holed catheter in place for twenty four hours, to a standard intravenous analgesia for small videoassisted thoracic surgery interventions. The objective is also to evaluate the resorption rate of local anesthetic at this level, and make a population pharmacokinetic analysis.

NCT ID: NCT03275428 Not yet recruiting - Thoracic Surgery Clinical Trials

THRIVE and Non-intubated Thoracic Surgery

Start date: September 11, 2017
Phase: N/A
Study type: Observational

Video assisted thoracic surgery utilizes small instruments to perform complicated thoracic surgeries. This minimally invasive technique leaves small wounds thus facilitate recovery. Traditionally, thoracic surgery required general anesthesia with double lumen endobronchial tube to facilitate one-lung ventilation. However, as anesthesia techniques improve, video assisted thoracic surgery can be achieved with minimal sedation and without intubation. Thoracic surgeries involve excision of lung tissue thus impair post-operative lung function, putting patients at high risk of cardiopulmonary complications. Non-intubate thoracic surgeries can avoid this complication by avoiding general anesthesia and intubation. Transnasal humidified rapid-insufflation ventilator exchange offers 30-50 L/min oxygen via nasal cannula, thus provide safe and comfortable way of oxygen supplementation. It is useful in intravenous sedated patients since they are prone to hypoxia from respiratory suppression and upper airway obstruction. This study is a matched case-control study to compare the efficacy and safety of Transnasal humidified rapid-insufflation ventilator exchange in non-intubated thoracic surgery versus double lumen endobronchial tube intubated general anesthesia.

NCT ID: NCT03261583 Completed - Thoracic Surgery Clinical Trials

Impact of Preoperative Martial Deficiency on the Level of Blood Transfusion in Programmed Cardiac Surgery

CARMATS
Start date: November 14, 2016
Phase:
Study type: Observational

Observational study.

NCT ID: NCT03230136 Completed - Thoracic Surgery Clinical Trials

Protection During Cardiac Surgery.

ProCCard
Start date: January 3, 2018
Phase: N/A
Study type: Interventional

This trial investigates whether a multimodal cardioprotection per-surgery therapeutic strategy could reduce myocardial injury in patients undergoing cardiac surgery compared to traditional management. The primary endpoint is the AUC (area under the curve) of the hypersensitive troponin I. Blood samples will be collected during the 72 hours following the aortic cross-unclamping. This trial is a French, multicenter, randomized, single-blinded and controlled trial. 210 patients will be enrolled with a clinical follow-up during 30 days.

NCT ID: NCT03184974 Completed - Thoracic Surgery Clinical Trials

Open Lung PEEP in Thoracic Surgery

Start date: October 1, 2015
Phase: N/A
Study type: Observational [Patient Registry]

During thoracic surgical procedures, while ventilating with a protective tidal volume, an open lung approach consisting of a recruitment maneuver followed by an individualized positive end-expiratory pressure (PEEP) titrated to best respiratory system compliance (Open-lung PEEP, OL-PEEP) would decrease driving pressure. To test this hypothesis, we performed a multicenter observational study in 17 Spanish teaching hospitals of patients undergoing one lung ventilation (OLV). In addition, we analyzed the association between the driving pressure and the prevalence of postoperative pulmonary complications (PPCs), and finally the association between the individualized PEEP and relevant patient preoperative or intraoperative variables.

NCT ID: NCT03177564 Recruiting - Thoracic Surgery Clinical Trials

Driving Pressure Limited Ventilation During Video-assisted Thoracoscopic Lobectomy

Start date: June 5, 2017
Phase: N/A
Study type: Interventional

This study aims to investigate the feasibility of a driving pressure limited mechanical ventilation strategy compared to a conventional strategy in patients undergoing one-lung ventilation during Video-assisted thoracoscopic lobectomy.

NCT ID: NCT03174743 Recruiting - Inflammation Clinical Trials

Protective Ventilation During Pulmonary Lobectomy

Start date: June 2, 2017
Phase: N/A
Study type: Interventional

The investigator will evaluate the influence of lung protective ventilation on postoperative clinical outcome in patients undergoing one-lung ventilation for pulmonary lobectomy.

NCT ID: NCT03165539 Recruiting - Delirium Clinical Trials

Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients

Start date: September 2015
Phase:
Study type: Observational

This study will assess the incidence and risk factors for post-operative delirium in patients undergoing thoracotomy. Specifically, the study will assess if there is any relationship between an intra-operative decrease in brain oxygen levels which can occur during one-lung ventilation, and the occurrence of delirium in the post-operative period.

NCT ID: NCT03158402 Completed - Thoracic Surgery Clinical Trials

Preoperative Inspiratory Muscle Training Effects on the Perioperative Inflammatory Reaction in Cardiac Surgery.

EMI HiPo
Start date: February 14, 2018
Phase: N/A
Study type: Interventional

This study evaluates the impact of preoperative high-intensity inspiratory muscle training (IMThi) before cardiac surgery on perioperative inflammatory response. Half participants will receive high intensity inspiratory muscle training and the others a sham inspiratory muscle therapy.

NCT ID: NCT03141216 Completed - Thoracic Surgery Clinical Trials

Patient-ventilator Asynchrony in Conventional Ventilation Modes During Short-term Mechanical Ventilation After Cardiac Surgery

Start date: March 9, 2017
Phase: N/A
Study type: Interventional

This study evaluates the effects of VCV, PCV and PSV ventilatory modes during the immediate postoperative period on the variables resulting from regional and global pulmonary electrical impedance and diaphragmatic mobility, as well as perform ventilator synchrony analysis in PSV mode by mechanical ventilator. Half of the participants will receive VCV followed by PSV for weaning, while the other half will receive PCV followed by PSV for weaning.