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Clinical Trial Summary

This is a preliminary, prospective interventional study to investigate the feasibility of using transcutaneous alternating current stimulation (TACS) and transcutaneous noninvasive vagal nerve stimulation (tnVNS) after a traumatic brain injury (TBI) to improve cognitive function and decision-making.


Clinical Trial Description

All participants engaged in the study will participate once weekly for six weeks at Hennepin Healthcare Systems, Inc. (HHS). Each participant will be randomized into the block design of sham or tACS/tnVNS during the first three appointments or the last three appointments. While participating, both the tACS and tnVNS will be applied in accordance with the manufacturer's suggested use. Participants will complete computer-based tasks, while taking part in either the sham or tACS/tnVNS stimulation. The study is investigating the use of neuromodulation after Traumatic Brain Injury (TBI) for improved cognitive function. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05327829
Study type Interventional
Source University of Minnesota
Contact David Darrow, MD
Phone 612-873-7481
Email Darro015@umn.edu
Status Not yet recruiting
Phase Early Phase 1
Start date April 30, 2024
Completion date April 30, 2027

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