Pharmacological Intervention in Depression After Traumatic Brain Injury

Status Completed

Clinical Trial Summary

The purpose of this study is to determine if treatment with venlafaxine reduces symptoms of depression in persons with traumatic brain injury.

Clinical Trial Description

The study evaluates the benefits of a promising antidepressant medication for the treatment of persons with traumatic brain injury (TBI) and major depressive disorder (MDD). The study is a randomized, double-blind, placebo-controlled trial of venlafaxine (a serotonin and norepinephrine reuptake inhibitor, also known as Effexor). Venlafaxine has been well established in the treatment of MDD in healthy individuals and is a recommended depression treatment agent for persons with TBI. By using a rigorous scientific methodology, this study will be an important first step in advancing the treatment of depression in this population beyond general impressions to proven treatments. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00205491
Study type	Interventional
Source	Virginia Commonwealth University
Contact
Status	Completed
Phase	Phase 4
Start date	October 2004
Completion date	September 2007

View Details

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