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Tachycardia, Ventricular clinical trials

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NCT ID: NCT02784912 Not yet recruiting - Heart Failure Clinical Trials

Biomarkers in Risk Stratification of Sustainted Ventricular Tachycardia or Electrical Storm After Ablation

STORM
Start date: September 2017
Phase: N/A
Study type: Observational [Patient Registry]

Prevalence of HF reaches 1-2% of developed populations, and consequently a significant problem becomes more frequent occurrence of ventricular arrhythmias (VA) - sustained ventricular tachycardia (sVT) and electrical storm (ES) requiring radiofrequency ablation. The aim of the study is to create a model of risk stratification to identify patients with increased risk of occurrence of composite (cardiovascular death or rehospitalization, arrhythmia recurrence) and secondary (inadequate device therapy, all-cause death or rehospitalization, intensification of atrial arrhythmia) endpoints after ablation of ES or sustained VT. Model will be based on additional measurements of N-terminal pro brain natriuretic peptide (NT-proBNP), Galectin-3, suppressor of tumorigenicity 2 (ST2), high sensitive troponin T (hs-TnT), high sensitive C-reactive protein (hs-CRP), iron deficiency to clinical-, electrocardiographic- and echocardiographic assessment.

NCT ID: NCT02780947 Not yet recruiting - Heart Failure Clinical Trials

Prophylactic Substrate Ablation in Post-myocardial Patients Undergoing Defibrillator Implantation.

Start date: June 2016
Phase: N/A
Study type: Interventional

Prophylactic substrate ablation in post-MI patients undergoing defibrillator implantation reduces appropriate defibrillator therapies.

NCT ID: NCT02761343 Completed - Clinical trials for Ventricular Tachycardia

MRI Assessment of Arrythmia Ablation Lesions

Start date: April 2014
Phase: N/A
Study type: Interventional

This study will evaluate the feasibility of visualization and characterization of arrhythmia ablation lesions by MRI immediately following standard ablation techniques. The appearance of the ablation lesion will be correlated with clinical outcomes and risk of arrhythmia recurrence.

NCT ID: NCT02666742 Completed - Stroke Clinical Trials

DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation

STROKE-VT
Start date: February 16, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to learn if taking a drug called direct oral anticoagulant after an ablation procedure keeps blood clots from forming and lowers the chance of having a stroke in patients with ventricular tachycardia or arrhythmia (VT).

NCT ID: NCT02661048 Completed - Clinical trials for Tachycardia, Ventricular

CyberHeart's Cardiac Arrhythmia Ablation Treatment: Patients With Refractory Ventricular Tachycardia/Fibrillation

Start date: February 27, 2015
Phase: N/A
Study type: Interventional

The objective of this clinical investigation is to evaluate: 1. the safety and efficacy of the CyberHeart System, CardioPlanā„¢ Software and Laptop, in treating patients with refractory ventricular tachycardia (VT) using the CyberKnife® Radiosurgical System. 2. The CyberHeart System performance with respect to the ability to contour myocardial targets that are transferred to the Multi-plan® Treatment Planning Software of the CyberKnife® system for the production and delivery of a safe radiosurgical treatment plan. Cardiac radiosurgery is a minimally-non invasive, painless, procedure. Tissue ablation can be accomplished precisely.

NCT ID: NCT02646501 Not yet recruiting - Clinical trials for Refractory Ventricular Tachycardia

Prospective Randomized Clinical Trial for Effect of Stellate Ganglion Block in Medically Refractory Ventricular Tachycardia

Start date: March 2019
Phase: N/A
Study type: Interventional

The investigators will compare the effects of PSGB(percutaneous stellate ganglion block) in patients with recurrent sustained VT/VF in spite of appropriate medical therapy and cardio-version/ defibrillation after correction of underlying correctable factors with those without PSGB by prospective randomized trail. PSGB will be performed every 3 days by anesthesiology specialist after cardiologist's request, until the stabilization of VT/VF. We will compare the frequency and episode number of VT/VF, procedure related complication, acute and long-term mortality.

NCT ID: NCT02637947 Terminated - Clinical trials for Tachycardia, Ventricular

Comparison of VT Ablation Outcomes Using Remote MAGNETIC Navigation Versus Manual Approach in a Low LVEF Population

MAGNETIC-VT
Start date: January 2016
Phase: N/A
Study type: Interventional

The study purpose is to demonstrate that ventricular tachycardia (VT) ablation using the Niobeā„¢ ES system results in superior outcomes compared to a manual approach in subjects with ischemic scar VT in a low ejection fraction population.

NCT ID: NCT02606071 Active, not recruiting - Heart Failure Clinical Trials

Italian Registry On Multipoint Left Ventricular Pacing

IRON-MPP
Start date: August 2013
Phase: N/A
Study type: Observational [Patient Registry]

The IRON-MPP is a prospective multicenter, observational registry designed to collect clinical and device data from a large cohort of HF patients treated in clinical practice with a CRT-D device with the ability to deliver Multi Point Pacing. The purpose of the Registry is to collect data on how MPP-devices are being used by physicians in order to better understand how to improve the clinical care of patients and effectiveness of MPP therapy.

NCT ID: NCT02584595 Withdrawn - Clinical trials for Monomorphic Ventricular Tachycardia

Evaluation of Inducible Monomorphic Ventricular Tachycardia (MMVT) in Patients With St. Jude Medical (SJM) Implantable Cardioverter Defibrillator (ICD) Systems or Cardiac Resynchronization Therapy Defibrillation (CRT-D) Systems.

EPIC
Start date: September 2015
Phase:
Study type: Observational

The intent of this observational study is to understand the role of non-invasive programmed stimulation (NIPS) to induce substrate based MMVT (Monomorphic Ventricular Tachycardia) in patients receiving new St. Jude Medical Implantable Cardioverter Defibrillator (ICD) or Cardiac Resynchronization Therapy Defibrillation (CRT-D) systems.

NCT ID: NCT02501005 Terminated - Clinical trials for Ventricular Tachycardia

Preventive aBlation of vEntricular tachycaRdia in Patients With myocardiaL INfarction

BERLIN VT
Start date: July 20, 2015
Phase: N/A
Study type: Interventional

The BERLIN VT study is designed to evaluate the impact of prophylactic ventricular tachycardia (VT) ablation on all-cause mortality and unplanned hospital admission for congestive heart failure or symptomatic ventricular tachycardia/ventricular fibrillation (VF) when compared to VT ablation after the third appropriate implantable cardioverter-defibrillator (ICD) shock.