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Tachycardia, Ventricular clinical trials

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NCT ID: NCT05097170 Completed - Clinical trials for Cerebral Oxygenation

Cerebral Oxygenation and Awareness During VT Ablation

Start date: November 1, 2021
Phase:
Study type: Observational

It is aimed to examine the effect of the decrease in blood pressure that occurs during the ventricular tachycardia ablation process on cerebral oxygenation and awareness. Patient's age, cardiac measurements (ejection fraction-EF), basal vital values, procedure time (especially activation and pacing mapping), and localization of the arrhythmia, may affect the NIRS and BIS response to blood pressure drop. In addition to the effects of patients' demographic information, cardiac capacity and procedure time on NIRS and BIS values (downtrend and duration), correlations of these values with other monitoring parameters (ETCO2 and SpO2) intended to be displayed.

NCT ID: NCT05086510 Completed - Clinical trials for Tachycardia, Ventricular

Ablation Targets of Scar-related Ventricular Tachycardia Identified by Dynamic Functional Substrate Mapping

Start date: October 28, 2021
Phase: N/A
Study type: Interventional

This study aims at comparing the recurrence rates of ventricular tachycardia ablated after being mapped by 2 different techniques.

NCT ID: NCT04983797 Completed - Clinical trials for Paroxysmal Atrial Fibrillation

A Study Assessing Arrhythmia Mapping With the Multi-Electrode OPTRELLâ„¢ Mapping Catheter

OPTIMUM
Start date: August 25, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the performance and safety for the use of the OPTRELL Catheter for intracardiac mapping in the atria and ventricles.

NCT ID: NCT04918303 Completed - Clinical trials for Ventricular Tachycardia

Skin Sympathetic Nerve Activity and Cardiac Arrhythmia

SKNA
Start date: May 3, 2021
Phase: N/A
Study type: Interventional

Sympathetic tone is important in cardiac arrhythmogenesis. The simultaneous recording of sympathetic nerve activity (SNA) and electrocardiogram (ECG) was obtained by invasive method. The purpose of this protocol is to further develop this recording method to turn it into a new non-invasive tool for arrhythmia prediction and detection. This method may also be useful in validating the results of surgical procedures aimed at sympathetic denervation

NCT ID: NCT04884100 Completed - Atrial Fibrillation Clinical Trials

enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening

enHEART
Start date: September 15, 2021
Phase: N/A
Study type: Interventional

This research will investigate the PPG signal morphology related to physiological and non- physiological changes in arrhythmia-related heart rate as well as the performance of the PPG-based features previously developed within the framework of the Mini-Holter study to discriminate between several cardiac arrhythmias. To this end, clinical data will be recorded on patients by using a wrist-based PPG monitor simultaneously with 12-lead ECG and intracardiac electrogram (EGM) signals at the university hospital in Lausanne. Importantly, this study will remain purely observational as it will not change the diagnostic and therapeutic management of the included patients, nor will it interfere with the time course of the procedures. The aim of enHEART study is to validate on a larger database the ability of several previously developed PPG-based features to detect a variety of cardiac arrhythmias.

NCT ID: NCT04747353 Completed - Clinical trials for Ventricular Tachycardia

Computed Tomography Targets for Efficient Guidance of Catheter Ablation in Ventricular Tachycardia (MAP-IN-HEART)

MAP-IN-HEART
Start date: May 4, 2021
Phase: N/A
Study type: Interventional

The hypothesis of MAP IN HEART is that catheter ablation for post-infarction ventricular tachycardia (VT) can be largely improved through a direct definition of primary ablation targets from pre-operative CT scan imaging. The objective of is to demonstrate that catheter ablation of post-infarction VT targeting left ventricular wall thickness channels as defined from CT scan is feasible and associated with favorable efficacy, efficiency and safety profiles. A single-arm prospective cohort study will be conducted, including 40 patients over 3 European centres. Baseline, procedural and 6-month follow-up data will be analyzed

NCT ID: NCT04712136 Completed - Clinical trials for Hypertrophic Cardiomyopathy

Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations

QUALIMYORYTHM
Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The QUALIMYORYTHM trial is a multicentre controlled study, aiming to assess health-related quality of life (HRQoL) of 107 children aged 6 to 18 years old with inherited cardiac arrhythmia (long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, or arrhythmogenic right ventricular dysplasia), or inherited cardiomyopathies (hypertrophic, dilated, or restrictive cardiomyopathy), and to compare the results to those of 107 age and gender-matched healthy subjects. The secondary objective is to assess, in this population, the HRQoL according to disease characteristics, level of physical activity, exercise capacity, and socio-demographic data. Participants will wear a fitness tracker for 2 weeks.

NCT ID: NCT04691089 Completed - Clinical trials for Ventricular Tachycardia

Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm

DEFI-2022
Start date: January 18, 2021
Phase:
Study type: Observational

In the Paris (France) Medical Emergency system, in the early phase of Out-of-hospital Cardiac Arrest (OHCA), the treatment of a Ventricular Fibrillation (VF) consists of delivering an External Electric Shock (EES) by a rescuer with the use of an Automated External Defibrillator (AED). This latter realizes a cardiac rhythm analysis every two minutes. This analysis requires that chest compressions (CC) be interrupted for a while. However, CC interruptions are potentially harmful due to the brain, and heart perfusions decrease. On the other hand, the recurrence of VF occurs mostly during the first minute after the shock, whereas the delay between 2 rhythm analysis is 2 minutes. The consequence is excessive time spent in VF, which is deleterious in terms of coronary and cerebral perfusion. The investigator implements a new AED algorithm whose operating principle is as follows. One minute after an EES administration, the AED realizes a cardiac rhythm analysis during which the rescuers do not need to interrupt the chest compressions (CC): this is called the rhythm analysis " in presence of CC" The detection of a VF " in presence of CC " needs to be confirmed, " in absence of CC " The CC's are therefore interrupted for new rhythm analysis. Once the presence of VF is approved, the AED proposes a shock to be administred The aim of the study Study Design: This is a prospective observational study. The eligibility criteria are as follows: - Patients in Out-Of-Hospital Cardiac Arrest. - Basic Life support care with an AED. The primary endpoint is the " chest-compression fraction (CCF) " that represents the CPR-time performance during the ten first minutes of BLS care ( or < 10 min in case of Return Of Spontaneus Circulation (ROSC))

NCT ID: NCT04675957 Completed - Heart Failure Clinical Trials

Cardiac Rehab Retrospective Review (CR3)

CR3
Start date: February 1, 2021
Phase:
Study type: Observational

All patients enrolled in the Austrian LifeVest Registry will be retrospectively screened for successfully completed ambulatory or stationary rehabilitation program. Baseline characteristics, complete rehab data, outcomes and follow up data, as well as wearable cardioverter defibrillator(WCD)-derived data will be collected from these patients. Specifically, performance data from the start of the exercise training (ET) will be compared to the end of ET; including type of training, exertion, time and duration will be collected. In addition, WCD recorded data such as automatically and manually recorded ECGs, compliance, and TRENDS data will be collected.

NCT ID: NCT04657705 Completed - Heart Diseases Clinical Trials

Application of High Power Radio Frequency Energy in the Ventricular Tachycardia Treatment

Start date: December 5, 2020
Phase: N/A
Study type: Interventional

Background: Patient's freedom from VT after RFA remains non-optimal and it depends on many factors. One of them is the effective reduction of the myocardium with RF energy during the operation. The standardization of the parameters of RF will help to increase the success of the procedure. Hypothesis: Radiofrequency ablation of ventricular tachycardias with high power parameters has comparable safety and leads to greater efficacy (absence of ventricular tachycardias and all types of cardioverter-defibrillator therapies) in the long-term compared with ablation with standard parameters in patients with structural heart disease. Purpose: to evaluate the safety and the efficiency of ablation of ventricular tachycardia in patients with structural heart disease using high power RF energy.