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Tachycardia, Supraventricular clinical trials

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NCT ID: NCT01426425 Completed - Heart Disease Clinical Trials

Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia

Start date: May 2012
Phase: Phase 3
Study type: Interventional

ICY-AVNRT (Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia) is a prospective multi-center, nonrandomized, single arm, controlled, unblinded, investigational clinical study. The purpose of this clinical study is to demonstrate the safety and effectiveness of the Freezor® Xtra Cardiac CryoAblation Catheter for the cryoablation of the conducting tissues of the heart in the treatment of patients with atrioventricular nodal reentrant tachycardia (AVNRT) using an endocardial approach.

NCT ID: NCT01382953 Completed - Atrial Fibrillation Clinical Trials

The Simple ECG Monitoring Trial (Comparison of a Novel Recording System With a Standard Holter Monitor)

Start date: August 2011
Phase: N/A
Study type: Observational

The purpose of this research is to simplify the standard recording system of the heart rhythm. The investigators desire to improve the ease of monitoring the cardiac rhythm for 24 hours. The investigators intent is to use a very small, innovative monitoring patch system that relieves the patient of wearing a cumbersome and uncomfortable recording system. This research trial will carry the title "The Simple ECG Monitoring" for Comparison of a Sternal ECG Recording System with a Standard ECG Recording System for Holter Monitoring. The data from the investigational device is for comparative purposes only. It will not be used by medical personnel for study subject treatment or diagnostic purposes.

NCT ID: NCT01223469 Completed - Atrial Fibrillation Clinical Trials

TOCCATA - Touch+™ for Catheter Ablation

TOCCATA
Start date: September 2008
Phase: N/A
Study type: Interventional

The main objective of this study is to demonstrate the clinical safety of a contact force sensing RF ablation catheter when used for the treatment of supraventricular tachycardia and atrial fibrillation. In addition, the study will characterize the use and value of contact force measurement during ablation, and the long term success (12 months) of the ablation procedure using this technology.

NCT ID: NCT01222156 Recruiting - Clinical trials for Tachycardia, Ventricular

Accuracy and Safety Study of the Magnetecs CGCI System for Intracardiac Mapping

RICTAM
Start date: October 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The Magnetecs Catheter Guidance Control and Imaging (CGCI) system is a magnetic remote navigation system which is comprised of a magnetic chamber of eight electromagnets around the patient torso. The system can change the magnetic field almost instantaneously and enables almost real time manipulation of a special magnetic catheter (Maxwell mapping catheter) which results in accurate, repeatable, rapid and safe target acquisition within the four chambers of the human heart. The trial is a prospective, non-randomized, clinical one designed to test the study hypotheses of (a) technical equivalence of the study device in comparison to other magnetic remote navigation systems, (b) performance equivalence or non-inferiority of the study device target acquisition capability compared to presently used catheter navigation techniques, and (c) safety equivalence or non-inferiority of the study device in comparison to catheter navigation devices using other navigation techniques.

NCT ID: NCT01216501 Terminated - Clinical trials for Supraventricular Tachycardia

Sevoflurane and Isoflurane for RF or Cryo Ablation in Children.

Start date: November 2011
Phase: N/A
Study type: Observational

In children, radiofrequency catheter ablation (RFCA) or cryoablation are highly effective treatments for supraventricular tachycardia treatment. General anesthesia is often required to ensure comfort during the prolonged procedure and to assure immobility in order to facilitate accurate mapping and subsequent ablation of the accessory pathway and/or arrhythmogenic focus. Successful anesthetic management of this patient population requires adequate suppression of sympathetic responses during the procedure while electrophysiological parameters remain unaltered for mapping purposes and subsequent ablation. Although Sevoflurane (SEVO) and Isoflurane (ISO) are two commonly used and evaluated volatile anesthetic agents for ablation procedures, comparison of those agents has not been performed previously not in adults, not in children. Hypothesis Time required for basic EP intervals, successful induction of SVT and successful RFCA or cryoablation in children will not be different between patients undergoing Sevoflurane or Isoflurane-based anesthesia.

NCT ID: NCT01132274 Completed - Clinical trials for Supraventricular Tachycardias

Radiation Exposure Reduction in Supraventricular Tachycardia Ablation

NO-PARTY
Start date: December 2009
Phase: Phase 4
Study type: Interventional

Radiofrequency catheter ablation (RFCA) is the mainstay of therapy for supraventricular tachyarrhythmias, providing cure in a high percentage of cases. Conventional ablation techniques require the use of fluoroscopy to place and navigate catheters in the heart, thus exposing patients to ionizing radiations with an additional risk of cancer. The feasibility and safety of a non-fluoroscopic RFCA of a wide range of supraventricular arrhythmias using the EnSite NavX mapping system have been recently reported. The NO-PARTY is a multicenter, randomized-controlled trial designed to test the hypothesis that supraventricular arrhythmias RFCA through the non-fluoroscopic EnSite NavX mapping system results in a clinically significant reduction of the exposure to ionizing radiations compared with conventional ablation techniques. NO-PARTY trial will determine whether supraventricular tachyarrhythmia RFCA through a non-fluoroscopic EnSite NavX mapping system is a suitable and cost-effective approach to achieve a clinically significant reduction of ionizing radiation exposure for both the patient and the operator.

NCT ID: NCT00979303 Completed - Clinical trials for Supraventricular Tachycardia

Using Non-Fluoroscopic Imaging Devices to Decrease Radiation Exposure During Ablation of Supraventricular Tachycardia

Start date: January 9, 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the additional use of non-fluoroscopic imaging modalities can decrease the use of radiation exposure during standard ablation procedures for supraventricular tachycardia (SVT) in children.

NCT ID: NCT00787800 Completed - Atrial Fibrillation Clinical Trials

The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock

RAPTURE
Start date: November 2008
Phase: Phase 4
Study type: Interventional

The RAPTURE Study will determine whether dual chamber defibrillators with atrial prevention and termination therapies, minimized ventricular pacing, and remote monitoring will reduce the rate of inappropriate shocks and improve quality of life compared to optimally programmed back-up pacing only single chamber ICDs when used for primary prevention of sudden cardiac death

NCT ID: NCT00413712 Completed - Clinical trials for Supraventricular Tachycardia

Effectiveness of Calcium Channel Blockers and Adenosine in the Emergency Management of SVT

Start date: January 1997
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the efficacy and effectiveness of calcium channel blockers and adenosine in the treatment of Supraventricular Tachycardia.

NCT ID: NCT00390546 Completed - Clinical trials for Supraventricular Tachycardia

Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia

Start date: October 2006
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, multi-centered study to compare 6 months of medical treatment with digoxin or propranolol in infants with SVT Background: SVT is the most common sustained arrhythmia of infancy. Neither digoxin nor propranolol has been evaluated for pediatric use in a controlled trial in the context of SVT, yet both medications are used frequently. Specific aims of the study: To determine whether propranolol and digoxin differ in the: 1. Incidence of recurrent SVT in infants after 6 months of treatment with propranolol or digoxin 2. Time to first recurrence of SVT in infants treated with propranolol or digoxin. 3. Incidence of adverse outcomes in infants treated with propranolol or digoxin.