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NCT ID: NCT05867550 Completed - Clinical trials for Irritable Bowel Syndrome With Diarrhea

To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea

Start date: January 3, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare the efficacy of four different drugs in combination for management of irritable bowel syndrome (IBS)-associated diarrhea. The main question to answer is: - Is there a significant difference in effect of different drug combinations in management of irritable bowel syndrome with diarrhea? Participants will be divided into 3 treatment groups. - Each group will be given a combination of drugs for 2 weeks - At the end of study, efficacy of different drug combinations and their potential side effects will be compared between the treatment groups

NCT ID: NCT05863806 Completed - Clinical trials for Rotator Cuff Syndrome

Mulligan Mobilization vs Transverse Friction Massage in Rotator Cuff Syndrome

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The aim of this research is to determine the Effects of Mulligan Mobilization and Transverse Friction Massage in Rotator Cuff Syndrome. Randomized clinical trials will be done at Northwest General Hospital, Peshawar. The sample size is 42. The subjects were divided in two groups, with 21 subjects in Group A and 21 in Group B. Study duration was of 6 months. Sampling technique applied was Non probability Purposive Sampling technique. Both males and females of aged 30-70 years with rotator cuff syndrome from grade (0-3) were included. Tools used in the study are Visual Analogue Scale (VAS), Goniometer, and DASH (Disabilities of the Arm, Shoulder and Hand) questionnaire. Data was analyzed through SPSS 23.

NCT ID: NCT05863780 Completed - Clinical trials for Carpal Tunnel Syndrome

Comparison of Flexor Retinaculum Stretch and Carpal Mobilizations in Patients With Carpal Tunnel Syndrome.

Start date: March 10, 2022
Phase: N/A
Study type: Interventional

Comparison of flexor retinaculum stretch and carpal mobilizations in carpal tunnel syndrome patients.

NCT ID: NCT05861349 Completed - Clinical trials for Carpal Tunnel Syndrome

Median Nerve Stenosis in Carpal Tunnel Syndrome

Start date: November 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to test the new kind of ultrasound-based measurements in patients with carpal tunnel syndrome. The main questions it aims to answer are: - Do the measurements of the size of the median nerve at the point where it is maximally compressed accurately diagnose carpal tunnel syndrome? - May these measurements accurately tell how severe is the carpal tunnel syndrome? Participants will be asked to: - Undergo conduction studies of median and ulnar nerve. - Undergo ultrasound of the median nerve. - Fill out the Boston carpal tunnel questionnaire and a demographic questionnaire. Researchers will compare the group of patients with carpal tunnel syndrome with healthy volunteers to see if respective measurements differ significantly between groups.

NCT ID: NCT05859789 Completed - Clinical trials for Metabolic Syndrome in Women

EFFECT OF MEDITERRANEAN DIET ON SEXUAL FUNCTION IN WOMEN WITH METABOLIC SYNDROME

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Metabolic syndrome (MS) is a cluster of metabolic abnormalities that includes hypertension, central obesity, insulin resistance, type 2-diabetes and atherogenic dyslipidaemia (1). A woman's sexual health is associated with several psychological and interpersonal factors, and may be affected by aging and metabolic changes (2). Obesity, hypertension, dyslipidemia, and type 2-diabetes which are conditions frequently present in women with metabolic syndrome are considered risk factors for atherosclerosis and endothelial dysfunction which impairs tissue oxygenation and causes subsequent functional and structural damage to the female genital tract. A decrease in pelvic blood flow secondary to atherosclerotic disease leads to fibrosis of the vaginal wall and clitoral smooth muscle, eventually resulting in vaginal dryness and dyspareunia (3). Women with metabolic syndrome showed higher prevalence of sexual inactivity and low sexual desire, orgasm, satisfaction, and Female sexual function (FSFI) total score in respect to women without metabolic syndrome (4). There is a link between diet and sexual performance markers to get and maintain lubrication, orgasm, and frequency of sex, as food has a favourable or negative impact on sexual activity for both sexes at any age (5). The Mediterranean diet (Med Diet) is one of the most widely described and evaluated dietary patterns in scientific literature. It is based on the traditional foods that people used to eat in countries bordering the Mediterranean Sea, including France, Spain, Greece, and Italy. It is characterized by high intakes of vegetables, legumes, fruits, nuts, grains, fish, seafood, extra virgin olive oil, and a moderate intake of red wine (6). Previous studies proved that Kegel exercise raise the level of sexual satisfaction, as the pelvic floor muscle (PFM) specifically the pubococcygeus and iliococcygeus muscles are responsible for the rhythmic involuntary contractions during orgasm (7). According to the authors' knowledge, no prior research studied the effect of Mediterranean diet on sexual function in women with metabolic syndrome.

NCT ID: NCT05857475 Completed - COPD Clinical Trials

Efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

To evaluate efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome

NCT ID: NCT05851001 Completed - Clinical trials for Restless Legs Syndrome

Effects of Progressive Muscle Relaxation Exercises During Pregnancy

Start date: April 1, 2016
Phase: N/A
Study type: Interventional

Participants were allocated into three groups; the control group, progressive muscle relaxation (PMR) group and relaxation music (RM) group. The PMR and RM programs were explained toall participants, and the first program was tested under the supervision of the researcher. PMR and RM group participants performed the program daily throughout 4 weeks. Severity of RLS with the International Restless Leg Syndrome Scale (IRLSS) and sleep quality with the Pittsburgh Sleep Quality Index (PSQI) were assessed at baseline, 2 and 4 weeks for all the groups.

NCT ID: NCT05848063 Completed - Piriformis Syndrome Clinical Trials

Effects of Global Hip Versus Isolated Abductors Strengthening Exercises in Patients Withsecondary Piriformis Syndrome

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

The study will be a randomized controlled trial. Twenty-four subjects will be assigned randomly by using the lottery method into two groups. Group A will be given a hot pack in addition to the global hip muscles strengthening exercise while group B is the control group which will receive a hot pack in addition to hip abductor strengthening. The time duration will be 6 weeks. Pain intensity will be assessed by NPRS.3 sessions per week will be given for 6 weeks. Outcome measures will be taken at baseline, in 3rd week, and at the end of the 6th week.

NCT ID: NCT05842200 Completed - Clinical trials for Patellofemoral Pain Syndrome

Influence of Selected Lower Limb Biomechanical Variables on Pain, Disability and Balance in Women With PFPS.

Start date: June 10, 2023
Phase:
Study type: Observational

Purpose: The aim of this study is to figure out how does the selection of lower-extremity biomechanical variables presented by dynamic knee valgus, tibial torsion and navicular drop may influence pain, disability, and balance in women with patellofemoral pain syndrome. Methods: Sixty-five women with patellofemoral pain syndrome will be evaluated for lower limb biomechanical variables.

NCT ID: NCT05840692 Completed - Clinical trials for Polycystic Ovary Syndrome

The Effect of Escitalopram in PCOS

Start date: August 2013
Phase: Phase 4
Study type: Interventional

In a randomized study the investigators aim to characterize the effect of antidepressive medicine on quality of life, body composition, adrenal activity and glucose metabolism in PCOS. PCOS is a common endocrine disorder characterized by adrenal and ovarian hyperandrogenaemia, anovulation and insulin resistance. The pathogenesis of PCOS may be described by a vicious cycle involving insulin resistance which stimulates ovarian and adrenal hyper androgenaemia and leads to abdominal obesity, causing increased risk for diabetes and cardiovascular disease. Adrenal hyperactivity is associated with depression. Antidepressive medicine may normalize pituitary-adrenal activity and in animal studies antidepressive medicine improved adrenal hyperactivity and normalized insulin sensitivity.