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Surgical Wound Dehiscence clinical trials

View clinical trials related to Surgical Wound Dehiscence.

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NCT ID: NCT03777774 Completed - Clinical trials for Surgical Site Infection

Subgaleal Drains in Decompressive Craniectomies

VADER
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This research is about the use of subgaleal drains to prevent accumulation of blood under the skin in patients undergoing surgery to remove part of the skull(craniectomy) and its associated complications. There have been early research that shows usage of subgaleal drains maybe related to increase in complication rates after craniectomy. These complications include hydrocephalus (accumulation of fluid in the brain), new hemorrhages, infection and low blood pressure. The investigators are performing this research to determine which type of subgaleal drains would produce the least complications. With this knowledge, the investigators would be able to reduce the amount of complications for future patients that undergo surgery to remove part of the skull. The purpose of this study is to determine the rate of complications in the 3 different groups of patients using the different types of drains under the skin in surgeries that involve removal of part of the skull. All participants will undergo the required surgery to remove part of the skull (craniectomy). Participants will then be randomly assigned to either one of 3 groups which are the vacuum drain group, passive drain group or no drain group.Participants in the vacuum drain group will have vacuum drains inserted during the closing stage of the surgery. Participants in the passive drain group will have passive drains inserted during the closing stage of the surgery. Participants in the no drain group will have a drain inserted during the closing stage of the procedure but the drain will remained closed. Data will then be collected and analysed to determine if the type of drains influence the rate of complications in craniectomy

NCT ID: NCT03716687 Terminated - Clinical trials for Surgical Site Infection

Prophylactic Negative Pressure Wound Therapy for High Risk Laparotomy Wounds. A Randomized Prospective Clinical Trial.

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Negative pressure wound closure technique (NPWT) has been widely introduced in different clinical settings. Most of the studies report it as an effective and cost-effective method to treat complicated surgical wounds or even open abdomen. NPWT as a prophylactic effort to prevent complications of high risk surgical wounds has recently been introduced, but the concept is still lacking clinical evidence in terms of clinical effectiveness and cost effectiveness. In this randomized, multi centric study investigators aim to compare prophylactic negative pressure wound closure (ciNPWT) with traditional, dry wound dressing at high infection risk laparotomy wounds.

NCT ID: NCT03649308 Active, not recruiting - Wound Heal Clinical Trials

Negative Pressure Wound Therapy Compared to Traditional Care After Skin Grafting

TRUTH
Start date: September 19, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to compare negative pressure wound therapy to traditional care after split-thickness skin grafting in patients aged over 18.

NCT ID: NCT03293862 Completed - Clinical trials for Surgical Wound Dehiscence

Prevention of Fascial Dehiscence With Prophylactic Onlay Mesh in Emergency Laparotomies

Start date: June 2015
Phase: N/A
Study type: Interventional

Facial dehiscence elicit high morbidity and mortality. This complication may arise in more than 8.5% of high-risk patients. Addressing risk factors and optimizing surgical technique are guarded as mainstay measures for prevention, but their efficacy is questionable. The aim of this study is to analyze the influence of using a polypropylene onlay prophylactic mesh on the incidence of fascial dehiscence in emergency surgery and associated complications.

NCT ID: NCT03008265 Active, not recruiting - Clinical trials for Postoperative Wound Breakdown

Fascial Dehiscence and Mortality

Start date: December 2016
Phase: N/A
Study type: Observational

Nationwide cohort study on short- and long-term mortality of patients with and without postoperative fascial dehiscence. The cohort will be comprised of patient undergoing open colonic resection for colonic cancer registered in the Danish Colorectal Cancer Group Database. The exposure is fascial dehiscence and the outcome of interest 30-day, 3- and 5-year mortality.

NCT ID: NCT02879487 Completed - Clinical trials for Surgical Wound Dehiscence

Vaginal Cuff Dehiscence at Total Laparoscopic Hysterectomy

Start date: August 2016
Phase: N/A
Study type: Interventional

The aim of this study is to assess a major complication of total laparoscopic hysterectomy, vaginal dehiscence, with two different colpotomy techniques. With this aim patients to be operated for laparoscopic hysterectomy will be randomized to two different techniques. The colpotomy will be undertaken by 'cut mode' in the first group and 'coagulation mode' in the second group. All of the operations will be preformed by the same surgical at a university hospital. Vaginal dehiscence after surgery is the primary outcome measure.

NCT ID: NCT02581904 Enrolling by invitation - Clinical trials for Peripheral Arterial Disease

Prevena Vascular Groin Wound Study

Start date: January 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if the application of a negative pressure dressing intraoperatively (Prevena; KCI, Inc) to vascular groin incisions decreases the wound complication rate in high risk patients.

NCT ID: NCT02565043 Completed - Clinical trials for Surgical Wound Dehiscence

The Clinical Efficacy of RENASYS TOUCH NPWT System in the Management of Acute, Sub-acute and Chronic Wounds

NPWT
Start date: April 2015
Phase: N/A
Study type: Interventional

The study is looking at the clinical efficacy, functionality and device performance of a new Negative Pressure Wound Therapy (NPWT) system in the management of a variety of wound types, in a real-life clinical setting. The study will comprise a prospective, open-labeled, multi-center study in a number of care-settings (both hospital and community) in South Africa. The patient's reference wound will be randomized to treatment with either intermittent or continuous NPWT mode to assess whether the delivery of NPWT via each of these therapy settings will have an effect on the rate and quality of wound healing.

NCT ID: NCT02467998 Recruiting - Burns Clinical Trials

Negative Pressure Wound Therapy Registry

NPWTR
Start date: January 2005
Phase:
Study type: Observational [Patient Registry]

The goal of the Negative Pressure Wound Therapy Registry (NPWTR) for Wounds is to provide real world patient data from electronic health records submitted to meet Stage 2 Meaningful Use in order to understand the effectiveness and safety of various NPWT devices and methods among patients with chronic wounds and ulcers. Randomized, controlled trials to establish product efficacy routinely exclude patients with the co-morbid conditions common to patients seen in usual clinical practice and thus the results of these Randomized Controlled Trials (RCTs) tend to be non-generalizable. Little is known about the effectiveness of NPWT among typical patients. Patient registries are also ideal for assessing long term safety issues in these devices.

NCT ID: NCT02453165 Completed - Clinical trials for Surgical Wound Dehiscence

Vaginal Cuff Dehiscence Following Total Laparoscopic Hysterectomy: Laparoscopic vs. Transvaginal Cuff Closure

Start date: February 1, 2015
Phase: N/A
Study type: Interventional

Post-hysterectomy vaginal cuff dehiscence is a rare but threatening complication. The investigators will compare transvaginal versus laparoscopic closure of the vaginal vault at the end of a total laparoscopic hysterectomy, in order which of these two modalities of suturing is associated with a lower risk of dehiscence.