Wound Heal Clinical Trial
Official title:
Negative Pressure Wound Therapy Compared to Traditional Care After Split-thickness Skin Grafting - a Randomized Controlled Trial
The aim of this study is to compare negative pressure wound therapy to traditional care after split-thickness skin grafting in patients aged over 18.
Split-thickness skin grafting (STSG) is one of the most commonly used techniques in reconstructive plastic surgery and dermatology. Skin grafts are being used to cover skin defects caused by multiple etiologies. Traditionally, patients are immobilized in bed or in wheelchair for up to five days after surgery. Long immobilization decreases patients overall ability to function and increases the length of the stay in hospital. Negative pressure wound therapy (NPWT) have been used successfully in treatment of acute, chronic and diabetic ulcers. It is proposed that NPWT increases capillary blood flow, decreases bacterial contamination, seroma formation and swelling. Using NPWT on split-thickness skin grafts after burns is well documented. It increases skin graft take ratio and speeds up healing. Aim of this study is to compare NPWT to traditional treatment after STSG for any indication in patients aged 18 to 99. This is a two-arm, multicenter, randomized prospective trial with 160 patients. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05023135 -
DeepView SnapShot Portable (DV-SSP): Device Training Study
|
||
| Recruiting |
NCT03459547 -
Soft Peri-implant Tissue Around Different Abutment Materials
|
N/A | |
| Recruiting |
NCT05608187 -
Evaluating Safety and Biological Effect on Wound Healing of ILP100-Topical in Subjects With Diabetic Foot Ulcers
|
Phase 2 | |
| Recruiting |
NCT04596124 -
Effectiveness and Tolerability of Fitostimoline Plus Cream and Gauze vs Connettivina Bio Plus Cream and Gauze
|
N/A | |
| Completed |
NCT03285542 -
Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty
|
N/A | |
| Recruiting |
NCT05474911 -
PILONIDAL SINUS: CONVENTIONAL CARE VERSUS NEGATIVE PRESSURE THERAPY.
|
N/A | |
| Recruiting |
NCT05689775 -
Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap
|
||
| Recruiting |
NCT04849143 -
The Effectiveness of Stingless Bee Honey (Kelulut Honey) Versus Gel in Diabetic Wound Bed Preparation
|
N/A | |
| Completed |
NCT03596112 -
The Difference in Wound Size Reduction Comparing Two Frequently Used Wound Dressings in Everyday Care
|
N/A | |
| Recruiting |
NCT05169814 -
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
|
Early Phase 1 | |
| Completed |
NCT04545476 -
Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities
|
N/A | |
| Completed |
NCT06020157 -
Comparison of Simple and Continuous Suture Techniques in Oral Surgery
|
N/A | |
| Recruiting |
NCT05133570 -
Study Evaluating the Effectiveness of Treatment With Vista Care®, in Arterial Ulcers of the Lower Extremities
|
||
| Recruiting |
NCT04901325 -
Baricitinib in the Treatment of Adults With Pyoderma Gangrenosum (PG)
|
Phase 2 | |
| Withdrawn |
NCT03668665 -
Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh - A Study in "Split Wound Design"
|
Phase 3 | |
| Completed |
NCT03703479 -
Effect of A-PRF After Removal of Wisdom Teeth
|
N/A | |
| Recruiting |
NCT03204851 -
Microlyte Dressing in the Management of Wounds
|
N/A | |
| Recruiting |
NCT06117436 -
Impact of Cilostazol Versus Cilostazol and Selenium Combination on the Healing of Diabetic Foot Ulcer Patients
|
Phase 2/Phase 3 | |
| Recruiting |
NCT05618912 -
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
|
N/A | |
| Completed |
NCT05252260 -
Comparison of Diode Laser-Assisted Vestibuloplasty And Conventional Vestibuloplasty
|
N/A |