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Surgical Procedures, Operative clinical trials

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NCT ID: NCT04002128 Completed - Stomach Neoplasms Clinical Trials

Tracheal Colonization and Outcome After Major Abdominal Cancer Surgery

Start date: January 2008
Phase: N/A
Study type: Interventional

The goals of this study were to investigate whether two anesthesia regimens, with and without N2O, and bacterial colonization influence respiratory complications after major abdominal surgery for cancer.

NCT ID: NCT03805230 Completed - Clinical trials for Surgical Procedures, Operative

Postoperative Vasopressor Usage: SQUEEZE

SQUEEZE
Start date: October 5, 2020
Phase:
Study type: Observational

A prospective multi-centre international observational study of postoperative vasopressor use, designed to answer the question: 'What is the proportion of patients that receive vasopressor infusions? In the management of these patients; - Are there variations in the practice between clinicians, hospitals or countries? If yes, are they associated with clinical outcome? - What are the health economic impacts associated with receiving vasopressors?

NCT ID: NCT03731039 Completed - Pain, Postoperative Clinical Trials

Postoperative Pain in Adult Patients.

Start date: September 21, 2017
Phase:
Study type: Observational

Each surgical intervention associated with even a minor tissue injury is a source of pain which needs to be effectively controlled. Although the Polish national guidelines for post-operative pain management have been published, many patients experience moderate and severe pain in the postoperative period. The aim of this study is (1) to assess pain severity among adult patients after different types of surgeries; (2) to identify demographic and clinical factors associated with postoperative pain.

NCT ID: NCT03694899 Completed - Clinical trials for Surgical Procedures, Operative

The Excess Opioid Disposal Study

Start date: October 3, 2018
Phase: N/A
Study type: Interventional

This study is designed to test the hypothesis that providing information to patients about excess opioid disposal, calling patients prior to their outpatient post-operative surgical appointment and providing a convenient drop box for opioid disposal will increase rates of FDA compliant disposal.

NCT ID: NCT03330236 Completed - Delirium Clinical Trials

EEG - Guided Anesthetic Care and Postoperative Delirium

EMODIPOD
Start date: October 13, 2017
Phase: N/A
Study type: Interventional

The study is a prospective, double blinded, randomized and controlled parallel trial to investigate the effect of the anesthetic care guided by EEG monitor (SedLine) on postoperative delirium. EMODIPOD = Electroencephalography Monitoring tO Decrease the Incidence of PostOperative Delirium

NCT ID: NCT03266315 Recruiting - Infant, Newborn Clinical Trials

Probiotics Supplementation and Intestinal Microbiome in Neonates With Gastrointestinal Surgery

ProPS
Start date: December 3, 2022
Phase: N/A
Study type: Interventional

Congenital defects of the gastrointestinal tract commonly require surgical intervention in the neonatal period. Intestinal surgery during this critical period of microbiome acquisition results in aberrant colonization of the gastrointestinal tract by several pathways. Surgical stress is known to cause disruption of the gut barrier and increase intestinal permeability and bacterial translocation. This process triggers exaggerated immune responses that lead to inflammation and sometimes infectious complications. Post-operative use of antibiotics has been shown to potentiate the growth of pathogenic bacterial species Adults with abdominal surgery who received post-op probiotics reported a significant reduction in surgical site infection, urinary tract infection, and combined infection. Currently, probiotics used only in the non-surgical population of infants. The main objective of this study is to determine the impact of probiotics administration on the intestinal microbiome in neonates undergoing intestinal surgery.

NCT ID: NCT02975375 Completed - Mortality Clinical Trials

The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery

Start date: April 2002
Phase: N/A
Study type: Observational

The investigators will conduct a population-based study using health administrative data to evaluate the impact of preoperative geriatric consultation on postoperative outcomes in older patients having elective, non-cardiac surgery

NCT ID: NCT02809937 Completed - Delirium Clinical Trials

Dexmedetomidine and Long-term Outcome in Elderly Patients After Surgery

Start date: May 2011
Phase: Phase 4
Study type: Interventional

Delirium is a frequent postoperative complication. Its occurrence is associated with worse long-term outcomes. In a previous randomized controlled trial, prophylactic low-dose dexmedetomidine infusion during the early postoperative period decreased the incidence of delirium in elderly patients after surgery. The purpose of this 3-year follow-up study is to evaluate whether prophylactic low-dose dexmedetomidine infusion can improve the 3-year outcome in elderly patients recruited in the previous randomized controlled trial.

NCT ID: NCT02768831 Completed - Clinical trials for Surgical Procedures, Operative

ETT Cuff Leak: TV Ratios

Start date: August 17, 2020
Phase: N/A
Study type: Interventional

In the past 5 years cuffed endotracheal tubes (ETT) have become the standard of care in pediatrics. However, hyperinflation of the cuff can compromise the tracheal mucosal perfusion while an inadequate seal may impact ventilation and potentially increase the risk of aspiration. Hence, the goal after placement of a cuffed ETT is to create a safe and effective tracheal seal. The two ways to measure that are to hold CPAP while listening for an audible leak and measuring the difference between the inspired and expired tidal volumes (TV). This is a prospective study to compare these two methods used to create a tracheal seal and measure the intracuff pressure after a satisfactory tracheal seal is established.

NCT ID: NCT02599233 Completed - Pain Clinical Trials

Characterization of Post-operative Pain Trajectories Over Seven Days and Links With Chronicity

PATCH
Start date: March 2016
Phase: N/A
Study type: Observational

The main objective of this study is to establish the postoperative "pain pathways" observed from D1 to D7 in the context of the current management after orthopedic, digestive, obstetrics and gynecology, urology, neurosurgery, vascular and thoracicn surgeries.