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Surgical Procedure, Unspecified clinical trials

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NCT ID: NCT03305666 Completed - Pneumonia Clinical Trials

Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures

Start date: October 5, 2017
Phase: Phase 4
Study type: Interventional

Rib fractures represent a common injury pattern this is highly associated with patient morbidity and mortality, as pain control remains a challenge. Even after surgical stabilization of rib fractures (SSRF), unsuccessful pain control can lead to morbid outcomes such as pneumonia and opioid dependence. Multi-modal anesthesia, with the use of thoracic epidurals and para-vertebral injections/catheters, has shown to lessen these occurrences but are subject to a wide array of limitations. A more directed therapy with liposomal bupivacaine has shown to provide sustained analgesia for up to 72 hours in patients who have undergone other types of thoracic surgery, but not SSRF. The hypothesis of the current clinical trial is that, among patients undergoing SSRF, liposomal bupivacaine delivered via video assisted thoracic surgery (VATS) is an intercostal nerve block that provides comparable analgesia to the pain catheter, as measured by pulmonary function, numeric pain scoring, and postoperative narcotic use.

NCT ID: NCT03299920 Completed - Orthopedic Disorder Clinical Trials

Opioid Consumption After Knee Arthroscopy

Start date: September 18, 2017
Phase: N/A
Study type: Interventional

This is a prospective, randomized trial of patients undergoing outpatient knee arthroscopy surgery and receiving a peripheral nerve block. Patients will be randomized to either receive standard discharge teaching or specialized teaching regarding pain control following a nerve block. Patients will be asked to complete a journal for 5 days recording their pain scores, opioid medication usage, and overall satisfaction with pain control at home.

NCT ID: NCT03230565 Completed - Pain, Postoperative Clinical Trials

Continuous Infusions vs Scheduled Bolus Infusions

Start date: June 1, 2018
Phase: Phase 4
Study type: Interventional

To compare continuous infusions to bolus infusions and there affect on post-surgical pain.

NCT ID: NCT03224884 Completed - Pain, Postoperative Clinical Trials

Interscalene Block Versus Supraclavicular Block for Shoulder Surgery

Start date: July 24, 2017
Phase: N/A
Study type: Interventional

Interscalene brachial plexus block constitutes the analgesic criterion standard for shoulder surgery. However it is associated with a high incidence of hemidiaphragmatic paralysis (HDP) that may not be tolerated by patients with chronic pulmonary disease. This randomized controlled trial will compare ultrasound-guided interscalene block (ISB) and supraclavicular block in patients undergoing arthroscopic shoulder surgery. The main outcome is static pain at 30 minutes after arrival in the post anesthesia care unit (PACU) as measured by a numerical rate scale (NRS) from 0 to 10. Our research hypothesis is that interscalene and supraclavicular blocks will result in equivalent postoperative analgesia at 30 minutes in the PACU. The equivalence margin is set at 2 points

NCT ID: NCT03107832 Completed - Clinical trials for Surgical Procedure, Unspecified

Thoracic Epidural Versus General Anaesthesia in Cholecystectomy

EVGAC
Start date: December 30, 2012
Phase: N/A
Study type: Interventional

CONTEXT AND AIMS: The aim of the study is to compare patients satisfaction of thoracic epidural and general anesthesia procedures in patients undergoing elective laparoscopic cholecystectomy. SETTINGS AND DESIGN: This comparative randomized study was conducted Abant Izzet Baysal University hospital between October 2012 and 2014.Forty-five patients who were under American Society of Anesthesiologists I-II classification and were scheduled for elective laparoscopic cholecystectomy were included in the study. SUBJECTS AND METHODS: All participant was separated, two group. In epidural anesthesia group(Group E), a catheter was installed and received 20 mg lidocaine hydrochloride, 15 mg bupivacaine, and 25 mg fentanyl citrate adjusted to 10 cc with normal saline to be injected by the epidural catheter. Bispectral index -controlled sedation was provided. In general anesthesia group(Group G), and induction was managed using 1.5 mg/kg fentanyl and 2 mg/kg propofol; 0.5 mg/kg rocuronium and sevoflurane in a 50% oxygen/air mixture was used. Blood gas analysis monitoring was performed in the 30th minute before and after pneumoperitoneum. Surgical satisfaction was recorded after pneumoperitoneum. After the operation, 75 mg diclofenac sodium was applied for patients with Numeric Rating Scale scores higher than 4. STATISTICAL ANALYSIS USED:Data analysis was performed using the Statistical Package for the Social Sciences version 18 software (SPSS, Chicago, IL, US). Descriptive variables, such as age, ASA classification, weight, height, mean arterial pressure (MAP), HR, and duration of surgery, are given as mean ± standard deviation, and an independent sample t-test (normal distribution) as well as a Mann-Whitney U test (not a normal distribution) were used for continuous variables. To compare the normal and abnormal distributions in the groups, simple t-test, and Wilcoxon test was used, respectively. The results were considered statistically significant at p-values <0.05.

NCT ID: NCT02943967 Completed - Clinical trials for Surgical Procedure, Unspecified

Corneal Cross-linking and Refractive Surface Ablation in Patients With Asymmetric Corneas

Start date: January 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate safety and efficacy of corneal cross-linking and photorefractive keratectomy for refractive correction in patients with bilateral asymmetric topography.

NCT ID: NCT02775344 Completed - Clinical trials for Surgical Procedure, Unspecified

3D Versus 2D Laparoscopic Ovarian Cystectomy

Start date: May 2014
Phase: N/A
Study type: Interventional

This is a prospective randomized study involving 80 patients. All participates will be given written information on 3D laparoscopy. They will be randomized according to computer-generated random sequence into two groups, 2D and 3D group. The operation will then be performed either using 2D or 3D laparoscopy. Surgeons are allowed to change to the other type of laparoscopy if difficulty encountered. After the operation, the surgeons will be required to fill in a questionnaire self-evaluating the performance using Global rating scale component of the intraoperative assessment tool (GOALS), any discomfort encountered, any need for change of laparoscopy and their preference on the type of laparoscopy. The level of complexity of the operation, duration of operation, blood loss and complications will be recorded.

NCT ID: NCT02771964 Completed - Quality of Life Clinical Trials

Assessing Change in Patient-reported Quality of Life After Elective Surgery: an Observational Comparison Study

Start date: January 2014
Phase:
Study type: Observational

This study will compare two commonly-used methods for assessing patient-reported quality of life. The first is to assess quality of life before surgery and again after surgery using the same validated scale (ie Veterans Rand 12). The second is simply to ask patients whether or not they think their post-operative quality of life is better, worse, or the same. The investigators hypothesize that the second method may be inaccurate due to cognitive bias.

NCT ID: NCT02691468 Completed - Clinical trials for Surgical Procedure, Unspecified

Displacement Between PVC and Silicon DLT

Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to compare difference of displacement between Polyvinyl Chloride(PVC) and Silicon double-lumen endobronchial tubes(DLTs) during changing position from supine to lateral in thoracic surgery.

NCT ID: NCT02626546 Completed - Clinical trials for Postoperative Complications

Predictors, Risk Factors and Outcome Following Major Surgery

PROFS
Start date: November 2015
Phase:
Study type: Observational

This is a multicentre, prospective, observational cohort study. Consecutive patients, operated in six University Hospitals in Sweden will be recruited following major surgical procedure. The length of patient recruitment period will be 12 weeks. The length of follow up will be 360 days . The objectives are to determine the postoperative morbidity (during the hospital stay), the survival (0-360 days), to identify risk factors for adverse outcomes and to identify risk factors that may potentially be influenced by any intervention in the future. Amendments: 1. The follow-up of mortality is extended to 3 years of the cohort 2. The mortality of the background population at 30 and 90 Days will be analyzed 3. Validation of the Surgical Outcome Risk Tool in the study cohort and in the background population are planned