Acute Kidney Injury After Cardiac Surgery on CPB

Surgery Clinical Trial

Official title:

Incidence of Acute Kidney Injury After Cardiac Surgery on Cardiopulmonary Bypass in the Pediatric Intensive Care Unit of Lausanne. A Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03513718
• Other study ID #: 2017-01542
• Status: Completed
• Start date: October 1, 2017
• Est. completion date: September 5, 2023

Study information

• Verified date: February 2024
• Source: Centre Hospitalier Universitaire Vaudois
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne, Switzerland.

Description:

The investigators will review in a retrospective way, all patients aged between 0 and 16 years, admitted in the PICU after cardiac surgery on CPB from 01.01.2014 to 31.12.2016. They will asses for AKI. The first step is to determine the incidence and severity, the second step is to determine the risk factors for AKI and/or protecting factors.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 250
• Est. completion date: September 5, 2023
• Est. primary completion date: September 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A to 16 Years

Eligibility

Inclusion Criteria:

• all pediatric patients (0-16 years) admitted to PICU after cardiac surgery with CPB.

Exclusion Criteria:

• Preexisting kidney injury,

• no preoperative creatinine lab value

Related Conditions & MeSH terms

• Acute Kidney Injury
• CBP
• Child, Only
• Congenital Heart Disease
• Heart Defects, Congenital
• Heart Diseases
• Surgery
• Wounds and Injuries

Locations

Country	Name	City	State
Switzerland	CHUV	Lausanne	Vaud

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire Vaudois

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Presence and severity of an AKI occurring during stay in the PICU	Scoring AKI with pRiffle	up to 3 month
Secondary	PICU stay and ventilation time	correlation between AKI and invasive ventilation/duration and PICU stay	up to 3 month
Secondary	Persisting AKI after release from PICU according to RIFLE score	After leaving ICU	more than 3 month