Surgery Clinical Trial
Official title:
Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Patients Undergoing Left Hemicolectomy: A Randomized Controlled Trial
The enhanced recovery after surgery and laparoscopic approach have been proven beneficial in surgery of the colon. However, patients have still pain, nausea and vomiting postoperatively. Postoperative pain is an expected but undesirable effect after an operation. This study will compare Transabdominis Plane (TAP) Block and Quadratus Lumborum (QL) Block with the common postoperative treatment with enteral and parenteral analgesics.
Status | Recruiting |
Enrollment | 75 |
Est. completion date | December 31, 2020 |
Est. primary completion date | December 31, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility |
Inclusion Criteria: - Age 18-80 Years - BMI 20-35 - ASA physical status I-II Exclusion Criteria: - Allergy to LA - Chronic pain requiring opioid analgesics - Patients with atrioventricular block II - Patients treated with class III antiarrhythmics - Patients with severe renal and/or hepatic disease - A coagulation disorder - An infection at the LA injection place |
Country | Name | City | State |
---|---|---|---|
Norway | Ostfold Hospital Trust, Moss | Grålum | Ostfold |
Lead Sponsor | Collaborator |
---|---|
Ostfold Hospital Trust |
Norway,
Blanco R, Ansari T, Riad W, Shetty N. Quadratus Lumborum Block Versus Transversus Abdominis Plane Block for Postoperative Pain After Cesarean Delivery: A Randomized Controlled Trial. Reg Anesth Pain Med. 2016 Nov/Dec;41(6):757-762. Erratum in: Reg Anesth — View Citation
Børglum J, Gögenür I, Bendtsen TF. Abdominal wall blocks in adults. Curr Opin Anaesthesiol. 2016 Oct;29(5):638-43. doi: 10.1097/ACO.0000000000000378. Review. — View Citation
El-Dawlatly AA, Turkistani A, Kettner SC, Machata AM, Delvi MB, Thallaj A, Kapral S, Marhofer P. Ultrasound-guided transversus abdominis plane block: description of a new technique and comparison with conventional systemic analgesia during laparoscopic ch — View Citation
Murouchi T, Iwasaki S, Yamakage M. Quadratus Lumborum Block: Analgesic Effects and Chronological Ropivacaine Concentrations After Laparoscopic Surgery. Reg Anesth Pain Med. 2016 Mar-Apr;41(2):146-50. doi: 10.1097/AAP.0000000000000349. — View Citation
Pirrera B, Alagna V, Lucchi A, Berti P, Gabbianelli C, Martorelli G, Mozzoni L, Ruggeri F, Ingardia A, Nardi G, Garulli G. Transversus abdominis plane (TAP) block versus thoracic epidural analgesia (TEA) in laparoscopic colon surgery in the ERAS program. — View Citation
Ueshima H, Otake H, Lin JA. Ultrasound-Guided Quadratus Lumborum Block: An Updated Review of Anatomy and Techniques. Biomed Res Int. 2017;2017:2752876. doi: 10.1155/2017/2752876. Epub 2017 Jan 3. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Use of analgesics - "change" is being assessed | Amount of analgesics used postoperative | 1 week (0-4 hrs) (4-24 hrs) (24-48 hrs) (48 - 168 hrs) | |
Secondary | Pain at the incision site - "change" is being assessed | VPS (Verbal Pain Score): No pain = 0, Slight pain = 1, Moderate pain= 2, Severe pain = 3 | 1 week (0-4 hrs) (4-24 hrs) (24-48 hrs) (48 - 168 hrs) | |
Secondary | Deep pain and pain on coughing - "change" is being assessed | VPS (Verbal Pain Score): No pain = 0, Slight pain = 1, Moderate pain= 2, Severe pain = 3 | 1 week (0-4 hrs) (4-24 hrs) (24-48 hrs) (48 - 168 hrs) | |
Secondary | Nonsteroidal anti-inflammatory drug consumption - "change" is being assessed | Amount of different medicaments in mg | 1 week (0-4 hrs) (4-24 hrs) (24-48 hrs) (48 - 168 hrs) | |
Secondary | Postoperative nausea and vomiting - "change" is being assessed | 0 - 3 score where None = 0, Little nausea = 1, Can not eat = 2, Vomiting = 3 | 1 week (0-4 hrs) (4-24 hrs) (24-48 hrs) (48 - 168 hrs) | |
Secondary | Antiemetic administered - "change" is being assessed | Amount of different medicaments in mg | 1 week (0-4 hrs) (4-24 hrs) (24-48 hrs) (48 - 168 hrs) | |
Secondary | Sedation scores - "change" is being assessed | Sleepy or active. Score: Awake = 0, Tired = 1, Falls asleep = 2, Asleep all the time = 3 | 1 week (0-4 hrs) (4-24 hrs) (24-48 hrs) (48 - 168 hrs) |
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