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N2 Lung Cancer Project: Neoadjuvant Treatment Followed Surgery Versus Chemoradiation

Surgery Clinical Trial

Official title:
Multicentric Retrospective Observation Study: Neoadjuvant Treatment and Surgery Versus Definitive Chemoradiation in the Non-Small Cell Lung Cancer (NSCLC) IIIA-N2

Clinical Trial Summary

The objective of this multicenter retrospective study is to compare overall survival in patients with stage IIIA-N2 NSCLC treated with neoadjuvant treatment and surgery versus definitive chemoradiation.

Secondary objectives are to analyze disease-free survival, median survival, locoregional and distant relapses as well as mortality and toxicity related to treatment.

Clinical Trial Description

Based on data published by the Intergroup 0139 trial, induction therapy followed by surgery in patients with stage IIIA-N2 NSCLC can increase overall survival compared to exclusive radical chemoradiation treatment.

The major handicap of all studies addressing the role of surgery in IIIA-N2 NSCLC is the difficulty of recruiting patients. Therefore, multicenter studies are necessary to confirm the hypothesis generated by the INT 0139. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02966769
Study type Observational
Source Grupo de Investigación Clínica en Oncología Radioterapia
Contact
Status Completed
Phase N/A
Start date June 2016
Completion date March 2017
View Details
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