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Surgery clinical trials

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NCT ID: NCT02938195 Recruiting - Surgery Clinical Trials

Phase II Study of Neo-adjuvant Chemoradiotherapy for Squamous Cell Esophageal Cancer

Start date: January 2016
Phase: Phase 2
Study type: Interventional

The investigators designed a new preoperative chemoradiotherapy regimen to focus on the most important radiation area and hope to reduce the radiation volume and try to reduce the postoperative mortality and treatment-related mortality.

NCT ID: NCT02905409 Recruiting - Surgery Clinical Trials

Study of Surgery in Patients With Idiopathic Macular Hole

Start date: August 31, 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the effects of two different internal limiting membrane peeling with distinct diameters after macular hole surgery on anatomical closure grades.

NCT ID: NCT02903719 Recruiting - Surgery Clinical Trials

The Effect of Phrenic Nerve Block on Postoperative Shoulder Pain in Patients for Liver Resection.

Start date: September 2016
Phase: Phase 4
Study type: Interventional

The aim of this study is to explore whether the use of ultrasound guided phrenic nerve block can reduce the postoperative pain in the shoulder after liver resection. The intervention is directed postoperative to the patients experiencing novel right sided shoulder pain.

NCT ID: NCT02893436 Recruiting - Surgery Clinical Trials

Time Prediction for Complete Recovery From Neuromuscular Blockade After Visual Recovery With Double Burst Stimulation

DBS PREDICTION
Start date: April 2014
Phase: N/A
Study type: Observational

The purpose is to calculate the time for an optimal recovery (T4/T1 > 0.9) from the moment when 2 responses to double burst stimulation are visually identical and this for 95% of patients.

NCT ID: NCT02887651 Recruiting - Surgery Clinical Trials

Cavity Boost Radiation Therapy vs. Observation in Cerebral Metastases After Complete Surgical Resection

C-O-MET
Start date: November 14, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a local fractionated radiation therapy achieves a better local tumor control after complete surgical metastases resection at 6 month as compared to observation alone. Further it should be evaluated if cognitive functioning and quality of life is similar in both groups.

NCT ID: NCT02857153 Recruiting - Surgery Clinical Trials

Effect of High vs. Low MAP Levels on Clinical Outcomes in Elderly Patients During Noncardiothoracic Surgery

Start date: July 2016
Phase: N/A
Study type: Interventional

This will be a multicentre, randomised, controlled and prospective clinical trial. All participants provided their written informed consent to participate in a randomized trial that examined the effects of low-level MAP (60-70 mmHg) vs. high-level MAP (90-100 mmHg) in elderly patients (65 or more years of age) during noncardiothoracic surgery under general anesthesia. The investigators hypothesise high-level blood presure of the intervention for reducing the incidence of post-operative complications.

NCT ID: NCT02800278 Recruiting - Surgery Clinical Trials

Characteristics and Outcomes of Odontoid Fragility Fractures in Elderly

FOOP
Start date: January 2016
Phase: N/A
Study type: Observational

Usually, cervical spine fractures are not considered as osteoporotic fractures. However, recent studies show that odontoid fractures are the most common fractures of the cervical spine in elderly and may occur in a context of low trauma energy. Thus, the goal of this observationnal study is : - to describe the different type of odontoid fracture and to characterize bone status in elderly patient (>65 y) who underwent odontoid fracture in a context of low trauma energy. - To describe short and long term outcomes

NCT ID: NCT02769754 Recruiting - Surgery Clinical Trials

Effectiveness of the Use of the New Hemostatic Patch Hemopatch ® in Patients Undergoing Surgical Liver Resection

HEMOPATCH
Start date: May 2016
Phase: Phase 3
Study type: Interventional

This prospective randomized study aims to determine the influence of the use of local hemostatic on the incidence of local complications derived from the edge of transection: biliary fistula or bleeding, after scheduled hepatic resection.

NCT ID: NCT02728427 Recruiting - Surgery Clinical Trials

Multicenter Study on Suprapubic Catheterization Versus Transurethral Catheterization in Laparoscopic Surgery for Rectal Cancer

MSSPC
Start date: April 2016
Phase: N/A
Study type: Interventional

Compared with traditional open proctectomy, laparoscopic surgery is associated with less pain, earlier recovery, and better cosmetic outcome, and its long-term oncologic outcomes have been demonstrated. However, the rate of urinary dysfunction after rectal cancer surgery was about 19-38% because of mesorectal excision. The type of drainage is unclear. Some studies show that the rates of urinary tract infection, second catheterization, and urinary symptom are lower with suprapubic catheterization (SPC) than with transurethral catheterization (TUC). Moreover,SPC allows for testing the bladder voiding without drainage removal. Furthermore,SPC using central venous catheter(CVC) is less invasive. Currently, there is lack of randomized controlled trial(RCT) to compare SPC with TUC. Therefore, investigators perform this prospective randomized trial to compare SPC using CVC with TUC in laparoscopic surgery for rectal cancer.

NCT ID: NCT02718365 Recruiting - Surgery Clinical Trials

Comparison Between Wedge Resection and Segmentectomy for Ground Glass Opacity- Dominant Stage IA NSCLC

Start date: December 7, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate whether the long-term outcome and safety of wedge resection are comparable to segmentectomy for the surgical treatment of early stage (IA) non-small cell lung cancer (NSCLC). Zhang et al. performed a meta-analysis of 53 studies and suggested that sublobectomy achieved a survival rate comparable to lobectomy in a selected population of patients with Stage I NSCLC. However, one critical question needs to be addressed, that is, does sublobectomy require segmentectomy or wedge resection? Cho et al. reported that, for pulmonary ground glass opacity (GGO) nodules (Stage IA NSCLC), wedge resection achieved a 5-year survival rate of 98.6% in the pure GGO group and 95.5% in the mixed GGO group. Cho et al. cautioned against performing wedge resection for mixed GGO nodules with GGO component ≤ 75%, due to the high recurrence rate. When radiology shows that the GGO component is ≥75%, pathology usually finds that the lesions are non-invasive. Therefore, these lesions are potential candidates for wedge resection. This randomized clinical trial is to assess whether wedge resection can be established as a standard treatment for Stage IA NSCLC with tumor size ≤ 2 cm and GGO component ≥ 75%.