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NCT ID: NCT04441957 Recruiting - Surgery Clinical Trials

MechanO-Chemical Ablation Versus CompreSSion

MOCASS
Start date: January 1, 2018
Phase:
Study type: Observational

This study will be looking at the effect of Endovenous Mechano-Chemical Ablation (MOCA) in addition to multilayer elastic compression bandaging vs multilayer elastic compression bandaging only in patients with incompetent great saphenous vein (GSV) and venous ulcers (VU's).

NCT ID: NCT04434274 Recruiting - Surgery Clinical Trials

MIcronized Flavonoid Fraction After MechanO-Chemical Ablation

MIFFMOCA
Start date: January 1, 2019
Phase:
Study type: Observational

This study will be evaluate the clinical efficacy of micronized purified flavonoid fraction (MPFF) phlebotropic therapy for postoperative pain, venospecific symptoms, and quality of life in patients with incompetent great or small saphenous veins (GSV/SSV) following an endovenous mechanochemical ablation procedure (MOCA).

NCT ID: NCT04434261 Recruiting - Surgery Clinical Trials

Oncological Surgery in Times of COVID-19: Effectiveness of Preoperative Screening for Sars-Cov-2

ASTANA
Start date: May 11, 2020
Phase:
Study type: Observational

To evaluate the incidence of patients with a positive test for SARS-CoV-2, performed in the preoperative screening for patients treated at the institution

NCT ID: NCT04428320 Recruiting - Surgery Clinical Trials

The Effect of Preemptive Levator Ani Injections on Pain After Pelvic Reconstructive Surgery

Start date: May 21, 2020
Phase: N/A
Study type: Interventional

Patients undergoing vaginal pelvic reconstructive surgery for pelvic organ prolapse (POP) under general anesthesia will be randomized to receive bilateral trans-vaginal pelvic floor muscle injections with bupivacaine or no injection (standard of care) as a part of their surgical pain control

NCT ID: NCT04425265 Recruiting - Surgery Clinical Trials

Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma

Start date: June 2020
Phase: N/A
Study type: Interventional

This study aims at exploring whether plasma radiofrequency ablation at low temperature is associated with better survival outcome in localized recurrent nasopharyngeal carcinoma by conducting a randomized controlled trial of plasma radiofrequency ablation at low temperature versus electrocautery block resection at high frequency for localized recurrent nasopharyngeal carcinoma. If the hypothesis is confirmed, it is expected to provide a convenient choice for the surgical treatment of localized recurrent nasopharyngeal carcinoma.

NCT ID: NCT04422054 Recruiting - Surgery Clinical Trials

Aneurysm Diameter and Surgical Outcome

ADASO
Start date: January 2, 2020
Phase:
Study type: Observational

Aneurysm diameter is an important risk for rupture and related death in affected patients. This study will evaluate whether aneurysms size may even influence post procedural outcomes both in open surgical repair and in end-vascular aneurysm repair. We will retrospectively review clinical data of operated patients with abdominal aortic aneurysm. We will consider both open surgical repair and endovascular aneurysm repair procedures in order to assess the influence of aneurysm size at the time of intervention.

NCT ID: NCT04416854 Recruiting - Surgery Clinical Trials

The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer

Start date: April 1, 2020
Phase: Phase 3
Study type: Interventional

The aim of this trial is to evaluate the value of palliative primary tumor resection in colon cancer patients with initially unresectable metastases and a positive response to induction chemotherapy which depends on gene testing. The primary endpoint is to evaluate overall survival.

NCT ID: NCT04406597 Recruiting - Surgery Clinical Trials

Safety, Effectiveness and Operability of Using the New Tissue Containment System During Laparoscopic Ovarian Cystectomy

Start date: May 20, 2022
Phase: N/A
Study type: Interventional

The study is designed to evaluate the safety, effectiveness and operability of performing in-bag cystectomy and morcellation with the new tissue containment system during laparoscopic ovarian cystectomy. Premenopausal women, aged 18-45 undergoing laparoscopic cystectomy.

NCT ID: NCT04402411 Recruiting - Surgery Clinical Trials

Quadratus Lumborum Block vs Transversus Abdominis Plane Block in Bladder Cancer Surgeries

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Transversus abdominis plane (TAP) block can be used to provide effective analgesia during the postoperative period following a range of surgeries. TAP block administers local anesthetics between the T6 to L1 spinal nerve roots to stop the nerve signal and to alleviate pain for abdominal procedures 4, 5. The viscera are innervated by the vagal nerve (parasympathetic innervation) and by the splanchnic nerves (sympathetic innervation). The splanchnic nerves carry both visceral efferent and afferent nerve fibers. The sensory (or afferent) part of the splanchnic nerves reach the spinal column at certain spinal segments, It is possible to block central visceral pain conduction with thoracic paravertebral blockade or maybe even with the novel quadratus lumborum (QL) block. The effect of the QL block is believed to result from a spread of LA from its lumbar deposition cranially into the thoracic paravertebral space (TPVS), since Carney et al found traces of contrast agent in the TPVS following application of this block. Hence, the QL block would seem to be able to alleviate both somatic and visceral pain.10 The aim of this study is to compare between quadratus lumborum block, transversus abdominis plane block regarding perioperative analgesia after bladder cancer surgeries by measuring intraoperative hemodynamics, postoperative pain scores and morphine consumption in the first 24 h postoperative.

NCT ID: NCT04395599 Recruiting - Surgery Clinical Trials

Risk of Air Contamination During Visceral Surgery in COVID19 Patients

COELIOCOVID
Start date: November 16, 2021
Phase: N/A
Study type: Interventional

Sars-Cov2 has been found in the digestive tract, as well as the respiratory tract. Protection of health care workers during surgery has been increased and some guidelines advocate for abandoning laparoscopy in COVID19 patients for fear of contamination, evenghtough this does not benefit the patient. However, Sars-Cov2 contamination risk during visceral surgery remains unknown. Inadequate protection is unnecessary costful and can be inefficient if too binding. Our hypotheses are that 1) Sars-Cov 2 can travel through droplet and air during visceral surgery. 2) Laparoscopy, because of the pneumoperitoneum and its leaks, warrant more air contamination whereas laparotomy warrant more droplet contamination, which would justified increased protection.