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Suicide clinical trials

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NCT ID: NCT05345184 Recruiting - Suicide Clinical Trials

Cognitive Behavioral Suicide Prevention for Psychosis: Aim 2

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Investigators will evaluate the feasibility and preliminary effectiveness of modified Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) in comparison to services-as-usual (SAU) in a randomized controlled trial. Investigators will recruit adult clients receiving services at a community mental health (CMH) setting who have a schizophrenia spectrum disorder and recent suicidal thoughts or behaviors within 3 months of screening (n=60). Client participants will be screened, enrolled and randomized to the CBSPp or SAU group. A 4-wave design will include quantitative assessments at baseline (T1), 1-month after baseline (T2), 3-months after baseline (T3), and 5-months after baseline (T4) with in-depth qualitative interviews at T3 for a random sample of adults in the CBSPp group (n=10). Providers (n=12) will be trained to deliver CBSPp and be assessed from T1-T3 to evaluate the implementation process, including in-depth qualitative interviews at T3.

NCT ID: NCT05325320 Recruiting - Stigmatization Clinical Trials

Intervention to Reduce Serious Mental Illness and Suicide Stigma Among Medical Students

Start date: April 6, 2022
Phase: N/A
Study type: Interventional

The team aims to develop and test the efficacy of a serious mental illness (SMI) and suicide ideation and attempt (SIA) stigma reduction intervention for medical students. The team expects that after intervention exposure, relative to control group, participants in the experimental condition will manifest more favorable change in knowledge, attitudes, and behaviors.

NCT ID: NCT05317481 Recruiting - Clinical trials for Major Depressive Disorder

Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to advance a non-pharmacologic suicide preventive intervention with wide dissemination potential as an innovative high-yield solution to reduce suicide rates. The investigators aim to achieve this with this study of Brain Emotion Circuitry Self-Monitoring and Regulation Therapy for Daily Rhythms (BE-SMART-DR), that provides self-directed strategies to regularize sleep and other DRs to reduce short-term suicide risk that can be used lifelong to potentially also reduce long-term suicide risk.

NCT ID: NCT05304065 Recruiting - Clinical trials for Suicide and Self-harm

Youth Partners in Care for Suicide Prevention

YPIC-SP
Start date: October 17, 2022
Phase: Phase 2
Study type: Interventional

This randomized comparative effectiveness trial will compare two evidence-based approaches to emergency care for youth ages 15-24 who present to the Emergency Department (ED) with suicidal ideation or behavior. OUtcomes will be monitored at baseline and at 3, 6 & 12 month follow-up assessments.

NCT ID: NCT05286112 Recruiting - Chronic Pain Clinical Trials

Mindfulness for Pain and Suicide

Start date: March 6, 2023
Phase: N/A
Study type: Interventional

The proposed study will assess the feasibility and acceptability of a mindfulness-based intervention to reduce functional impairment from chronic pain and risk of suicide.

NCT ID: NCT05282225 Recruiting - Suicide Clinical Trials

Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care

Start date: November 7, 2022
Phase: N/A
Study type: Interventional

This study is being completed to examine different combinations of technology-augmented strategies to identify an effective Adaptive intervention (AI) addressing post-discharge suicide risk with high implementation potential.

NCT ID: NCT05275101 Recruiting - Suicide Clinical Trials

Neural Mechanisms and Predictors of an Ultra-Brief Suicide Prevention Strategy

Start date: July 28, 2021
Phase: N/A
Study type: Interventional

The current study is a clinical trial, meaning a research study in which human subjects are prospectively assigned to one or more interventions to evaluate the effects of those interventions on health-related behavioral outcomes. Specifically, male and female adults with current suicidal intent will be randomly assigned to receive either a 1-hour session of crisis response planning (CRP) or a 1-hour session of standard crisis risk management (Treatment as Usual). The effects of both conditions on changes in emotion regulation, behavioral inhibition, stress reactivity, and suicide risk will be evaluated post-intervention and at six-month follow-up. Additional assessments of changes in mood and suicidality will be collected daily during the first 10-days following intervention, and then monthly for a duration of six months. A cohort of healthy controls is included in the study but are not randomized to either treatment condition. The investigators hypothesize the following: 1) A single session of CRP will acutely change suicide risk and 2) Individuals who receive CRP will show sustained improvements in measures of suicidality when compared to individuals who received the Treatment as Usual intervention.

NCT ID: NCT05272176 Recruiting - Suicide Clinical Trials

Veterans Coordinated Community Care (3C) Study

3C
Start date: January 11, 2022
Phase: N/A
Study type: Interventional

Veterans Coordinated Community Care (3C) Study will recruit 850 Veterans at risk for suicide post inpatient hospitalization. Each participant will be randomly assigned to treatment as usual (TAU) or TAU plus the Coping Long Term with Active Suicide Program (CLASP), with follow-up for 6 months after discharge. Outcomes include suicide-related behaviors (including deaths due to suicide, opioid overdose, or other substance-related accidents; and nonfatal suicide attempts) and suicidal ideation and functioning.

NCT ID: NCT05256940 Recruiting - Suicidal Ideation Clinical Trials

Motivational Interviewing to Address Suicidal Ideation for Veterans at High Risk for Suicide

MI-SI
Start date: November 30, 2022
Phase: N/A
Study type: Interventional

The purpose of this project is to conduct a randomized control trial with 470 Veterans to examine the impact of a revised version of Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) on risk for suicide attempts and suicidal ideation when compared to high quality usual care.

NCT ID: NCT05231213 Recruiting - Suicide Clinical Trials

Effects of Neuromodulation and Cognitive Training for Suicide in Veterans (ENACTS)

ENACTS
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Impaired executive function, such as impaired decision making and impulsivity, has been identified as an important contributor to the transition from suicidal ideation to suicide attempt. To address the epidemic of Veteran suicide in the United States, this study tests the feasibility, acceptability, and preliminary effectiveness of a five day transcranial direct current stimulation (tDCS) augmented executive functioning training intervention. This intervention is delivered to high suicide risk inpatients. The ultimate goal is to reduce future suicide events (ideation, attempts, deaths) and improve quality of life (e.g. social relationships, health resource utilization).